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Research Assistant - Department of Oncology - Georgetown University Medical Center
Job Overview
The Research Assistant uses advanced metabolomic tools for developing small molecule quantitation assays, preparation and analysis of biological samples for mass spectrometric analysis for supporting DoD (IARPA) funded project with a goal of developing MS based biomarker assays. Responsibilities include but are not limited to:
- Receive work instructions to analyze data, design, and develop methodologies necessary for accurate knowledge discovery.
- Participate on teleconferences to discuss experimental design with project collaborators for scientific coordination and data reporting on a periodic basis.
- Assist with successful completion of milestones as laid out in the grant, wherein the work includes optimization of MS sample preparation, developing small molecule quantitation assays, and designing MRM assays in accordance with GLP (Good Laboratory practices).
- Determine assay precision and accuracy and generate raw data on LC/MS instruments, perform Pre- and Post-processing the data using algebraic and statistical calculations in Excel and R and various software’s viz. XCMS, MetaboAnalyst, as well as database searches of metabolomic biomarkers in METLIN, LIPIDMAPS, HMDB, MMCD, generations of technical reports
- Schedules Mass spectrometry instrument operations and maintenance, performs data backup on a UIS drive, maintains laboratory in compliance with safety procedures, and administers general laboratory upkeep that includes autoclaving, scheduling waste disposal, and update of chemical inventory
- Perform validation studies using molecular and cellular biology techniques; and process and integrate high dimensional data generated using multi-omics approaches
Work Interactions and Work Mode Designation
Under the supervision of Dr. Amrita K Cheema, the Research Assistant uses advanced metabolomic and lipidomic tools for the preparation and analysis of metabolomics data. They receive work instructions to analyze data, design, and develop methodologies necessary for accurate knowledge discovery.
As well, they work closely with the team members in the laboratory and assist them with day-to- day laboratory wet and dry laboratory related functions.
This position has been designated as On Campus. Please note that work mode designations are regularly reviewed in order to meet the evolving needs of the University. Such review may necessitate a change to a position’s mode of work designation. Complete details about Georgetown University’s mode of work designations for staff positions can be found on the Department of Human Resources website: https://hr.georgetown.edu/mode-of-work-designation .
Requirements and Qualifications
- Bachelor’s degree or Master's degree in Chemistry/Biotechnology/Biochemistry/Computational biology or related field – preference for a doctoral degree
- Expertise in laboratory techniques, including but not limited to sample preparation, and molecular and cellular biology techniques such as cell culture, western blots, ELISA, RTPCR, and/or extracellular vesicle isolation
Preferred Qualifications
- Experience with quantitative and qualitative statistical analyses and tests
- Experience in analysis of mass spectrometry data
- Strong verbal and written communications skills
- Ability to multi-task
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Submission Guidelines:
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EEO Statement:
Georgetown University is an Equal Opportunity/Affirmative Action Employer fully dedicated to achieving a diverse faculty and staff. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, national origin, age, sex (including pregnancy, gender identity and expression, and sexual orientation), disability status, protected veteran status, or any other characteristic protected by law .
Benefits:
Georgetown University offers a comprehensive and competitive benefit package that includes medical, dental, vision, disability and life insurance, retirement savings, tuition assistance, work-life balance benefits, employee discounts and an array of voluntary insurance options. You can learn more about benefits and eligibility on the Department of Human Resources website .