Berkeley Lab’s Biological Systems & Engineering Division has an opening for a Postdoctoral Scholar. The candidate will combine machine learning , synthetic biology , and automation to make bioengineering a predictable endeavor , and enable the production of commercially viable bioproducts for the benefit of society. This position will be part of the Quantitative Modeling Group led by Hector Garcia Martin . Under general supervision of the principal investigator, the candidate will work as part of a collaborative team to integrate phenotypic data (e.g. fluxomics, transcriptomics, proteomics, metabolomics) into quantitative computational models able to predict the outcome of bioengineering approaches, as well as develop and apply automation solutions to gather these data. The candidate will be working closely with bench scientists, automation engineers and software developers in devising methods for high-throughput data collection and analysis for feedback into experimental design, as part of the Agile BioFoundry , the Joint BioEnergy Institute , or other programs.
What You Will Do:
Develop quantitative predictive models of cell metabolism.
Integrate transcriptomic, proteomic and metabolomic data into quantitative models.
Use and develop new machine-learning approaches to predict bioengineering outcomes.
Calculate fluxes through 13 C Metabolic Flux Analysis.
Develop and optimize code and algorithms for predictive models.
Develop automated experiments in collaboration with automation engineers to gather data for predictive models.
Interact continuously with bench scientist to guide and propose new experiments and use available data to its full potential.
Prepare research results for publication and for presentations at scientific and internal meetings.
Additional Responsibilities as needed:
Assist in preparation of grant proposals.
Perform 13C Metabolic Flux Analysis experiments.
Leverage Deep Learning techniques to solve computational biology problems.
What is Required:
Ph.D. in systems biology, bioengineering, computational biology, bioinformatics, applied mathematics, physics, computer science, electrical engineering or closely related discipline.
Significant experience in python or other major programming language.
Strong mathematical background and analytical skills.
Strong interest in microbiology and bacterial metabolism.
Strong written communication skills.
A commitment to and demonstrated ability to perform collaborative research in an interdisciplinary team environment.
Additional Desired Qualifications:
Experience in modeling of biological systems.
Experience in Machine Learning.
Experience in 13C Metabolic Flux Analysis.
Experience in experimental metabolic engineering bench work (e.g. construct design, gene knockout, cloning and expression ).
Experience in Deep Learning techniques.
Knowledge of microbiology and bacterial metabolism.
Experience in experimental bench work.
The posting shall remain open until the position is filled.
This is a full time 2-year postdoctoral appointment with the possibility of renewal based upon satisfactory job performance, continuing the availability of funds and ongoing operational needs. You must have less than 3 years of paid postdoctoral experience. Salary for Postdoctoral positions depends on years of experience post-degree.
Full-time, M-F, exempt (monthly paid) from overtime pay.
This position is represented by a union for collective bargaining purposes.
Salary will be predetermined based on postdoctoral step rates.
This position may be subject to a background check. Any convictions will be evaluated to determine if they directly relate to the responsibilities and requirements of the position. Having a conviction history will not automatically disqualify an applicant from being considered for employment.
Work will be primarily performed at Joint BioEnergy Institute (JBEI) — Bldg. 978, 5885 Hollis St., 4th floor, Emeryville, CA.
Berkeley Lab ( LBNL ) addresses the world’s most urgent scientific challenges by advancing sustainable energy, protecting human health, creating new materials, and revealing the origin and fate of the universe. Founded in 1931, Berkeley Lab’s scientific expertise has been recognized with 13 Nobel prizes. The University of California manages Berkeley Lab for the U.S. Department of Energy’s Office of Science.
Equal Employment Opportunity: Berkeley Lab is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status. Berkeley Lab is in compliance with the Pay Transparency Nondiscrimination Provision under 41 CFR 60-1.4. Click here to view the poster and supplement: "Equal Employment Opportunity is the Law."
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