Postdoctoral Scholar

East Carolina University, United States

Updated: about 2 years ago
Location: Greenville, SOUTH CAROLINA
Deadline: ;

Posting Details
Job Title Postdoctoral Scholar
Position Number PDS-ANAT-09-21
Vacancy Open to All Candidates
Department HSH BSOM Anatomy and Cell Biology
Department Homepage https://www.ecu.edu/Anatomy/
Advertising Department ANATOMY & CELL BIOLOGY
Division Health Sciences
Classification Title Postdoctoral Scholar
Working Title Postdoctoral Scholar
Number of Vacancies 1
Full Time Equivalent (FTE) 1.0
Full Time or Part Time Full Time
Salary Range $53,760
Position Location (City) Greenville
Position Type Postdoctoral Scholars
Job Category Postdoctoral Scholars
Primary Function of Organizational Unit
The Department of Anatomy and Cell Biology is dedicated to the discovery, development, and promotion of biomedical knowledge involving cell biology and the anatomical sciences of Gross Anatomy, Developmental Anatomy, Histology, and Neuroanatomy. Through this mission, we aim to improve human health through innovative educational programs and excellence in research and scholarly activities in a dynamic and diverse learning community. 
  
The Department of Anatomy and Cell Biology is located in the Brody Medical Sciences Building on the west campus of East Carolina University and has fifteen faculty, eight staff, two research fellows, two office support staff, and six to ten doctoral students. Our faculty are actively involved with research areas that include signal transduction; stem cells; educational models and distance learning; cellular senescence and determinants of radiosensitivity in cancer; rearrangements of the cytoskeleton that occur during spermatogenesis; role of delta-catenin, presenilin and cadherins in synaptic remodeling and in cancer; function of tight junctions and claudins in ionic and tissue homeostasis; hyaluronan-CD44 interactions and their influence on BMP-initiated Smad signaling and other signaling pathways; and CD44-initiated signaling pathways that result in enhanced MMP production and extracellular degradation. 
  
Throughout the brief history of the Brody School of Medicine at East Carolina University, the Department of Anatomy and Cell Biology has had an active role in training graduate students. Our former students now hold prestigious postdoctoral, faculty, and professional positions throughout the United States. In addition to our graduate program, we provide instruction to medical, nursing, physical therapy, and physician assistant students.
Job Duties
A position for a postdoctoral fellow is available in the laboratories of Drs. Maranke Koster and Peter Koch at Brody School of Medicine at East Carolina University. The overall goal of the research program is to investigate cellular and molecular mechanisms that underlie tissue fragility in patients affected by genetic skin disorders known as ectodermal dysplasias. To investigate these mechanisms, the postdoctoral fellow will use and further develop human stem cell-based models that have been established in our laboratory [patient derived induced pluripotent stem cell (iPSC) models; iPSC]. Specifically, the successful candidate will use our established methods to generate keratinocytes from our patient-derived iPSC. These keratinocytes will be used to analyze disease mechanisms using various OMICS and cell biological approaches. In addition, the successful candidate will be involved in the analysis of genetically engineered mouse models that replicate ectodermal dysplasia phenotypes. 
The successful candidate should have experience in cell culture as well as standard techniques in molecular and cellular biology. Candidates with experience in pluripotent stem cell culture and differentiation are preferred. Further, candidates with experience analyzing mouse model phenotypes are highly encouraged to apply. 
The postdoctoral scholar is responsible for independent and collaborative development, implementation, and analysis of scientific research in the discipline of Cell Biology. Responsibilities include management of all aspects of the project described above. Duties include: hypothesis development, literature review, collection of pilot data, report writing, and supervising of undergraduate research students and graduate research students, overseeing data collection procedures, supervising experimental procedures, review of data for quality control, supervision of data entry/data analysis, analysis of research hypothesis using descriptive and multivariate statistics, and the development of independent and collaborative presentations and publications. Scholars are expected to demonstrate compliance with established guidelines and regulatory standards for research including biosafety, responsible conduct of research and human subjects training. 
Approximately 85% of the postdoctoral scholar’s time will be devoted to performing research, preparing grants/manuscripts, and data reporting. Approximately 15% of the postdoctoral scholar’s time will be devoted to managing the day-to-day activity of undergraduate and graduate research students in the laboratory.
Minimum Education/Experience
PhD degree from an accredited college or university in Cell Biology, Molecular Biology, or a similar field
Minimum of 3 years research experience Prior successful working experience using a wide range of cell and molecular biology techniques
Excellent communication skills using the English language
The ability to work independently within the research laboratory
Excellent written and oral communication skills
License or Certification Required by Statute or Regulation
None
Preferred Experience, Skills, Training/Education
Experience in working with keratinocyte cultures or stem cell cultures.
License or Certification Required by the Department
Special Instructions to Applicant
To be considered for this position, all applicants must apply through PeopleAdmin and attach their CV or resume, cover letter and names and contact information of 3 references. Appointments are typically for a one-year period. Five years (typically five appointments of one year) is typically the maximum total period that any individual may serve as a Scholar. The University, in its sole discretion has the option to renew or extend any appointment, subject to the availability of funds, past performance evaluations and/or any other lawful reasons. For other information on the ECU Office of Postdoctoral Affairs, please visit our website at: https://rede.ecu.edu/postdoctoral/
Additional Instructions to Applicant

In order to be considered for this position, applicants must complete a candidate profile online via the PeopleAdmin system and submit any requested documents. Additionally, applicants that possess the preferred education and experience must also possess the minimum education/experience, if applicable.
Job Open Date 09/28/2021
Open Until Filled Yes
Job Close Date - Positions will be posted until 11:59 p.m. EST on this date. If no closing date is indicated, the position may close at any time after the initial screening date.
Initial Screening Begins 10/05/2021
Rank Level Not Applicable
Quick Link for Direct Access to Posting https://ecu.peopleadmin.com/postings/45207
AA/EOE
East Carolina University is an equal opportunity and affirmative action employer and seeks to create an environment that fosters the recruitment and retention of a more diverse student body, faculty, staff and administration. We encourage qualified applicants from women, minorities, veterans, individuals with a disability, and historically underrepresented groups. All qualified applicants will receive consideration for employment without regard to their race/ethnicity, color, genetic information, national origin, religion, sex, sexual orientation, gender identity, age, disability, political affiliation, or veteran status.
 
Individuals requesting accommodation under the Americans with Disabilities Act Amendments Act (ADAAA) should contact the Department of Human Resources at (252) 737-1018 (Voice/TTY) or ADA[email protected] .
Eligibility for Employment
Final candidates are subject to criminal & sex offender background checks. Some vacancies also require credit or motor vehicle checks. ECU participates in E-Verify. Federal law requires all employers to verify the identity and employment eligibility of all persons hired to work in the United States. If highest degree earned is from an institution outside of the U.S. and its territories, final candidates are required to have their degree validated as equivalent to the degree conferred by a regionally accredited college or university in the U.S.
Office of Human Resources Contact Information
If you experience any problems accessing the system or have questions about the application process, please contact the Office of Human Resources at (252) 328-9847 or toll free at 1-866-489-1740 or send an email to [email protected]. Our office is available to provide assistance Monday-Friday from 8:00-5:00 EST.

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