Postdoctoral Research Associate

Details

Posted: 04-Feb-24

Location: Princeton, NJ, US, 08540

Type: Full-time

Salary: Open

Categories:

Other Staff/Administrative

Internal Number: 236281223

Position: Postdoctoral Research Associate
Company: Princeton University
Description: Each of us harbor biological timers in our bodies known as the circadian clock. These clocks drive physiological processes and behaviors in coordination with the day-night cycle. Recent work has provided evidence that the circadian clock regulates immune functions in coordination with the day-night cycle. However, the underlying mechanisms by which the circadian clock drives rhythms in immunity are ill-defined. The Brooks lab seeks to mechanistically determine circadian clock regulation of innate immune functions at the intestinal epithelial barrier. Forming the first line of defense, the intestinal epithelium must acquire nutrients from the diet while maintaining harmony with a vast consortium of microorganisms known collectively as the microbiota. Endemic to the epithelium are specialized epithelial and immune cell types that produce antimicrobial proteins, bolster the epithelial barrier, and coordinate immune responses. These fundamental functions of innate immunity are regulated by the time of day. The Brooks lab is seeking a postdoctoral candidate or more senior researcher to characterize the impact of clocks across the intestinal epithelial barrier on host defense. The successful candidate will join a highly collaborative group with strengths in cell biology, mouse genetics, and molecular biology. The P.I. is dedicated to providing a nurturing training environment with the acknowledgment that mentorship must be tailored to the individual. The ideal applicant will be highly motivated; have a Ph.D. degree; research experience in one or more of the following cell biology, molecular biology, biochemistry, bioinformatics, genetics, immunology, and/or microbiology; Fluent in English language and writing skills. Experience with one or more of the following is a plus: Flow cytometry, electron microscopy, bioinformatics, microscopy, or bacterial genetics. This appointment is for one year with the possibility of renewal pending satisfactory performance and availability of funding. Applications from members of groups historically under-represented in molecular biology are strongly encouraged. To apply, please submit a cover letter, CV, and three letters of recommendation to: https://puwebp.princeton.edu/AcadHire/position/25401 Review of the applications will begin on May 1st and will continue until the position is filled. This position is subject to the University's background check policy. Informal inquiries are also welcome: email [email protected]. Princeton University is an Equal Opportunity/Affirmative Action Employer and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity or expression, national origin, disability status, protected veteran status, or any other characteristic protected by law. EEO IS THE LAW. No recruiters and no telephone calls please.

PI236281223

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About Princeton University
Princeton University is a vibrant community of scholarship and learning that stands in the nation's service and in the service of all nations. Chartered in 1746, Princeton is the fourth-oldest college in the United States. Princeton is an independent, coeducational, nondenominational institution that provides undergraduate and graduate instruction in the humanities, social sciences, natural sciences and engineering.As a world-renowned research university, Princeton seeks to achieve the highest levels of distinction in the discovery and transmission of knowledge and understanding. At the same time, Princeton is distinctive among research universities in its commitment to undergraduate teaching.Today, more than 1,100 faculty members instruct approximately 5,200 undergraduate students and 2,600 graduate students. The University's generous financial aid program ensures that talented students from all economic backgrounds can afford a Princeton education.
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