Job Description
Position Summary
Nanotechnology development for the treatment of malignant brain tumors.
Postdoctoral positions are available in the laboratory of Alexander H. Stegh, Ph.D., Scientific Director of the Brain Tumor Center, Washington University School of Medicine. The laboratory is currently seeking highly motivated and talented Postdoctoral Fellows to join the dynamic research team. The successful candidate will contribute to cutting-edge research in the development of immunostimulatory nanostructures. This position offers a unique opportunity to work on innovative projects aimed at advancing the field of brain tumor immunotherapy. Importantly, the ideal candidate is eager to learn and discover new forefronts of nanomedicine. The candidate is self-sufficient but team-oriented individual.
The ideal candidate will be proficient with the following:
- Design and synthesize novel immunostimulatory nanostructures for therapeutic applications.
- Conduct in vitro and in vivo experiments to evaluate the immunostimulatory properties of nanostructures.
- Collaborate with interdisciplinary teams to combine nanostructures with existing immunotherapeutic treatment.
- Handling of mice, tumor tissue and cell extractions.
- Strong background in cellular and molecular immunology and cancer biology, specifically of the brain, pancreas, and breast.
- Demonstrated experience in widely used immunological tools and assays such as flow cytometry, FACS, extraction and analysis of splenocytes with antibodies, and analysis of immune system cell stimulation and proliferation.
- Demonstrated expertise in immunology and molecular biology, as supported by peer-reviewed publications. Experience in the subjects of mouse tumor models, including syngeneic and transgenic models, and the generation of vectors and transformed cell lines (designed to probe humanized characteristics of tumors and immune system cells) are essential.
The Stegh group includes scientists with expertise in tumor immunology, biology, and the development and use of genetically engineered mouse models. Research topics center on the control of molecules and materials at the nanometer length scale, and the use of these materials in neuro-oncology applications.
Information on being a postdoc at Washington University in St. Louis can be found at https://postdoc.wustl.edu/prospective-postdocs-2/ .
Required Qualifications
Candidates must hold a Ph.D and/or M.D. degree (or anticipate receiving their degree in the near future).
Preferred Qualifications
- Ph.D. in Chemistry, Bioengineering, Immunology, or a related field.
- Strong background in nanotechnology, materials science, biomedical engineering, or a relevant discipline.
- Experience in the design and synthesis of nanostructures for biomedical applications.
- Proficiency in standard laboratory techniques, cell culture, and in vivo mouse studies.
- Excellent analytical and problem-solving skills.
- Demonstrated ability to work independently and collaboratively in a research team.
- Strong written and oral communication skills.
- Knowledge of immunology and experience with immunotherapeutic approaches.
- Expertise in characterizing nanostructures using advanced analytical techniques.
- Track record of publications in peer-reviewed journals.
Working Conditions
This position works in a laboratory environment with potential exposure to biological and chemical hazards. The individual must be physically able to wear protective equipment and to provide standard care to research animals.
Salary Range
Base pay is commensurate with experience.
Applicant Special Instructions
Interested candidates should send a cover letter, their C.V. and a list of two or three references to Professor Alexander Stegh: [email protected] .
Accommodation
If you are unable to use our online application system and would like an accommodation, please email [email protected] or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.
Pre-Employment Screening
All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.
Benefits Statement
Washington University in St. Louis is committed to providing a comprehensive and competitive benefits package to our employees. Benefits eligibility is subject to employment status, full-time equivalent (FTE) workload, and weekly standard hours. Please visit our website at https://hr.wustl.edu/benefits/ to view a summary of benefits.
EEO/AA Statement
Washington University in St. Louis is committed to the principles and practices of equal employment opportunity and especially encourages applications by those from underrepresented groups. It is the University’s policy to provide equal opportunity and access to persons in all job titles without regard to race, ethnicity, color, national origin, age, religion, sex, sexual orientation, gender identity or expression, disability, protected veteran status, or genetic information.
Diversity Statement
Washington University is dedicated to building a diverse community of individuals who are committed to contributing to an inclusive environment – fostering respect for all and welcoming individuals from diverse backgrounds, experiences and perspectives. Individuals with a commitment to these values are encouraged to apply.