Postdoctoral Positions in Bioinformatics and Computational Mass Spectrometry — Immunopeptidomics & T-cell vaccine targets discovery

Updated: about 11 hours ago
Location: New Haven, CONNECTICUT
Deadline: The position may have been removed or expired!

Postdoctoral Positions in Bioinformatics and

Computational Mass Spectrometry —

Immunopeptidomics & T-cell vaccine targets discovery

(Starting immediately or upon agreement)

Postdoctoral Positions in Etienne Caron Lab at Department of Immunobiology, Yale School of Medicine. The Caron Lab seeks postdoctoral applicants with a passion for innovation in mass spectrometry-based immunopeptidomics research. The overarching goal of the Caron Lab is to develop and apply mass spectrometry-based methods and systems immunology approaches to understand the generation, composition and dynamics of both the self and nonself immunopeptidome, as well as its interaction with T cells, with the ultimate goal of innovating treatments and preventive strategies for a broad range of immune-related diseases.

Expectations and Qualifications:

The successful candidates are expected to work on the development and application of bioinformatic (integrative multi-omic methods) and/or computational mass spectrometry workflows (machine- and deep-learning methods) for the analysis of immunopeptidomic data generated by a timsTOF Ultra (Bruker). We are seeking passionate individuals with a solid background in computational sciences who are already familiar with state-of-the-art packages and analysis pipelines in mass spectrometry-based proteomics and/or immunopeptidomics. Among the required qualifications are the following:

  • PhD in computer science, bioinformatics or a related field.
  • Work experience in proteomics and/or immunopeptidomics
  • Programing skills (Python, R, Java, C, C++).
  • Expert in GitHub user.
  • Strong communication skills in English (spoken and written).
  • Ability to work independently and collaboratively.

Opportunities and Benefits:

Postdocs will have the opportunity to gain expertise in mass spectrometry, systems immunology, spatial immunopeptidomics, T-cell epitope discovery, immunology, and vaccine design. The selected candidates will also have the opportunity to become active players within several Yale Centers, including the Yale Center for Immuno-Oncology (YCIO), Center for Infection and Immunity (CII), and Center for Systems and Engineering and Immunology (CSEI). Strong support will be given to purse independent directions. Postdoc compensation and benefits will be according to Yale policies. More information about salaries and other resources can be found at https://postdocs.yale.edu/.

About the Caron Lab:

Dr. Caron is an Assistant Professor at Yale who has recently moved from University of Montreal, Canada. Over the last five years, the Caron Lab has published 14 immunopeptidomics manuscripts including 10 as corresponding papers in Journal of Experimental Medicine, Cell Systems, Cancer Discovery, and other high-profile journals. Dr. Caron is co-founder and former chair (2015-2020) of the Human Immunopeptidome Project. He has a total citation of >4400 times to date and is the recipient of multiple Awards and Recognitions. Please see https://medicine.yale.edu/profile/etienne-caron/ for more information.

If interested, please send your CV and a motivation letter to [email protected].

Yale University is an Affirmative Action/Equal Opportunity Employer. Yale values diversity among its students, staff, and faculty and strongly welcomes applications from women, persons with disabilities, protected Veterans, and underrepresented minorities


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