Postdoctoral Fellow - Structural Biology

Join the forefront of groundbreaking research at the

where we're changing lives and making a real difference in the fight against cancer, diabetes, and other life-threatening illnesses. Our dedicated and compassionate faculty and staff are driven by a common mission: Contribute to innovative approaches in predicting, preventing, and curing diseases, shaping the future of medicine through cutting-edge research.

The laboratories of Dr. Jeff Perry, a Structural Biologist, and Dr. Javier Gordon Ogembo, a Vaccinologist, are currently seeking a highly motivated and talented individual to fill a postdoctoral position in the field of gamma-herpesvirus structural biology. The goal of the postdoctoral candidate will be to elucidate the mechanisms of gamma-herpesvirus entry and contribute to vaccine development. If you are looking for a challenging and exciting opportunity to advance your research career in oncogenic gamma-herpesviruses and cancer, we invite you to join our multi-disciplinary lab. For more information about Dr. Ogembo's lab, please visit here.

As a successful candidate, you will:

• Access state-of-the-art facilities and resources for transitional science in a vibrant, collaborative research community.
• Utilize FDA-approved facilities for producing investigational drugs and biologics for clinical trials.
• Work in facilities designed to meet rigorous regulatory standards, ensuring safety and efficacy of developed products.
• Seize the opportunity as a postdoctoral fellow to collaborate with leading experts, contributing to cutting-edge research in viral entry, oncovirology, and vaccinology.
• Explore interactions between viruses and host cells, advancing understanding in these crucial areas.
• Experience an exciting research environment, enhancing your career while contributing to impactful projects.

Your qualifications should include:

• A Ph.D., Ph.D/DVM, or Ph.D/MD degree(s) in a related field and a strong background in protein biochemistry and structural biology.
• Cell culture and aseptic technique: culture, handling, and maintenance of bacterial and mammalian cells (multiple cell lines), cryopreservation.
• Protein production and structural assays: protein expression in different cell systems and purification; protein crystallography and/or cryo-electron microscopy; circular dichroism (CD) spectroscopy, mass spectrometry, isothermal calorimetry and/or surface plasmon resonance.
• Immuno-assays: western blot, ELISA, flow cytometry, immunofluorescence assay, immuno-histochemistry.
• Molecular cloning and basic DNA/RNA assays: molecular cloning, DNA/RNA isolation from cells, conventional PCR.

• Experience in virology, cancer vaccines, T-cell immunology, and/or the use of animal models will be considered as a plus.
• Virology assays: virus production and titration, virus neutralization, plaque assays.
• Advanced DNA/RNA assays: DNA isolation from tissue, qPCR, RT-qPCR.
• Pre-clinical animal models: animal handling (mice and/or rats), immunization, blood collection, tissue processing.

City of Hope is an equal opportunity employer. To learn more about our commitment to diversity, equity and inclusion, please click here.