Details
Posted: 04-Apr-24
Location: New Brunswick, New Jersey
Salary: Open
Categories:
Research Support - Laboratory/Non-Laboratory
Staff/Administrative
Internal Number: 224981
Position Summary:
Rutgers, The State University of New Jersey, is seeking a Postdoctoral Fellow for NJMS- Microbiology, Biochemistry & Molecular Genetics. A postdoctoral fellow position is available in the Petrou lab at Rutgers-New Jersey Medical School (NJMS) to support NIH-funded research. Our research focuses on the structural biology of membrane proteins using single particle cryoelectron microscopy (cryo-EM). Our goal is to characterize the structure and function of bacterial membrane enzymes involved in antibiotic resistance, and eukaryotic receptors and enzymes relevant to human physiology and pathology. The Postdoctoral Fellow is responsible for the expression and purification of proteins using bacterial, insect and mammalian heterologous expression systems, and for the structure determination of membrane proteins and/or protein complexes by single-particle cryo-EM. In addition, the Postdoctoral Fellow is responsible for biophysical or biochemical characterization of target proteins, including protein-ligand or protein-protein interactions.
Among the key duties of this position are the following:
- Protein expression and purification – heterologous protein expression using bacterial, insect or mammalian systems, affinity purification, and chromatographic separation using FPLC and HPLC.
- Determination of three-dimensional structures of proteins using cryo-electron microscopy data and appropriate computational programs/resources (e.g. Relion, cryoSPARC, etc.).
- Collects, compiles and presents data with appropriate conclusions, recommendations, etc. pertinent to research activity.
- Communicates regularly with the Principal Investigator.
- Maintains detailed and accurate experimental records.
- Participates and presents in journal clubs, seminars and conferences.
- Prepares reports for peer-reviewed scientific publications, and contributes to grant writing
- Performs training of lab personnel in molecular biology, biochemistry and single-particle cryo-EM.
Minimum Education and Experience:
- Ph.D. in Structural Biology, Molecular Biology, Biochemistry, or related fields.
City: Newark
State: NJ
Physical Demands and Work Environment:
PHYSICAL DEMANDS:
Must be able to safely perform laboratory experiments. Must be able to lift a weight of 3kg up to waist level.
WORK ENVIRONMENT:
Research laboratory
Salary: Minimum salary $56,963
Posting Number: 24ST0771
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About Rutgers University
Rutgers, The State University of New Jersey, is a leading national public research university and the state's preeminent, comprehensive public institution of higher education. Rutgers is dedicated to teaching that meets the highest standards of excellence; to conducting research that breaks new ground; and to turning knowledge into solutions for local, national, and global communities. As it was at our founding in 1766, the heart of our mission is preparing students to become productive members of society and good citizens of the world. Rutgers teaches across the full educational spectrum: preschool to precollege; undergraduate to graduate and postdoctoral; and continuing education for professional and personal advancement. Rutgers is New Jersey's land-grant institution and one of the nation's foremost research universities, and as such, we educate, make discoveries, serve as an engine of economic growth, and generate ideas for improving people's lives.
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