The mission of our team is to translate novel drug-delivery technologies to treat children with brain tumors. The brain has a natural barrier that prevents toxins and other agents from reaching the brain. This same barrier also limits the access of systemic treatments, including chemotherapy, targeted therapy, and immunotherapy, from reaching the tumor. We are interested in exploring the usage of focused ultrasound (FUS) and convection-enhanced delivery (CED). Using targeted ultrasound, or FUS, with microbubbles, the blood-brain barrier (BBB) can temporarily and reversibly open to allow for enhanced drug delivery to fight brain tumors. In addition, we are also exploring the use of direct catheter delivery of drugs to brain tumors using CED. We are focusing on identifying novel methods to treat Pediatric Brain tumors using new Drug Delivery Approaches and novel agents. Our goal is to translate into Novel Clinical Trials for children suffering from brain tumors.
We are seeking candidates with experience in cell culture work, molecular biology, and preclinical tumor models. Successful candidates will be highly motivated individuals with a doctoral degree in Neurology, Oncology, or Immunology, have excellent communication skills, be able to function independently, and participate as part of a dynamic team. The successful candidate will be involved in generating preclinical data that will lead to the design a number of novel clinical studies in children with high-grade gliomas and other brain tumors.
Work Location:
Fralin Biomedical Research Institute at VTC, Roanoke, VA
https://fbri.vtc.vt.edu/
Documents Needed to Apply:
Curriculum Vitae
Cover Letter
List of References
If interested or have any questions regarding this position, please email [email protected].