POSTDOCTORAL ASSOCIATE - Pathology

Updated: 6 days ago
Location: Durham, NORTH CAROLINA

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

Occupational Summary

Conduct independent research activities under the guidance of a faculty mentor in preparation for a full time academic or research career.   Research will be supported by an NIH contract that aims to compare in vitro and in vivo activities of vaccine adjuvants tested by the sublingual route as a component of sublingual immunotherapy for peanut allergy in mouse models.

Work Performed

DEFINITION:

The Postdoctoral Appointee holds a PhD or equivalent doctorate (e.g. ScD, MD, DVM). Candidates with non-US degrees may be required to provide proof of degree equivalency.

EXPECTATION:

  • The conscientious discharge of research or scholarship responsibilities, which may include teaching responsibilities for Postdoctoral Associates
  • Conformance to standards of responsible conduct in research
  • Compliance with good scholarly and research practices of the Staats lab and compliance with Staats lab standard operating procedures and data management plans.
  • Perform cell culture based experiments to evaluate adjuvant activity in vitro based on measurement of adjuvant-stimulated cytokine/chemokine secretion.
  • Perform intranasal, intramuscular and/or sublingual immunization of mice with collection of blood and/or mucosal samples pre- and post-immunization.
  • Monitor antigen-specific, vaccine-induced antibodies (IgG, IgG subclasses, IgA, IgE) in samples collected from mice by ELISA.
  • Design and execute experiments and interpret the data.
  • Collaborate with other laboratory team members and the computational scientists.
  • Review raw data with the Staats lab members (lab meeting presentation) and prepare experimental summaries to share with the adjuvant comparison research team.
  • Maintain comprehensive laboratory records
  • Participate in the preparation of progress reports for submission to the NIH and manuscripts for submission to peer-reviewed journals.

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Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.


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