Details
Posted: 19-Feb-24
Location: Cambridge, Massachusetts
Type: Full-time
Salary: Open
Categories:
Academic/Faculty
Other - Academic/Faculty
Internal Number: 22391
Job Description
POSTDOCTORAL ASSOCIATE, Chemical Engineering (ChemE), to join an active lab and a project funded by FDA (Development of an Integrated Continuous cGMP Facility for mRNA Manufacturing). Will conduct research in the intersection of mechanistic modeling and systems engineering. Responsibilities will include designing feedback/feedforward control systems for continuous mRNA manufacturing, including model predictive control of the end-to-end manufacturing system while taking disturbances and model uncertainties into account; and building mechanistic models and control systems for multiphase flow-based nanoparticle formation; and perform other duties as assigned. The models will be constructed for a process involving multiple liquid streams containing multiple components that impinge on each other in either laminar or highly turbulent flow to create a nanoemulsion in a confined environment. The modeling for the nanodroplets that are formed will then model the transition of the nanodroplets into the formation of solid lipid nanoparticles. The controls will be for the characteristics of the nanoparticles. The faculty supervisors are Professor Richard D. Braatz and Professor Allan Myerson.
Job Requirements
REQUIRED: Ph.D. in chemical engineering or related field and the ability to manage projects and meet deadlines. PREFERRED: experience in experimental and simulation tools for biopharmaceutical process development, including for biotherapeutic antibodies. Job #22391
This is a sponsored research position for the period of one year with the possibility of an extension.
2/17/23
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