School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.
Job Description
A Postdoctoral position supported by Michael J. Fox foundation (MJFF) and the Aligning Science Across Parkinson’s (ASAP) is available to study gut to brain mechanisms in Parkinson’s disease. The project will involve cutting-edge experimental therapeutics in novel mouse models, ex vivo organoid research, and advanced pathological analysis of abnormal conformations of the protein alpha-synuclein. This three-year training opportunity is led within the West laboratory in the Duke Center for Neurodegeneration and Neurotherapeutic research in the new Medical Sciences Research Building III, opened in late 2018. Recent post-doctoral fellows transitioning from the West laboratory have received competitive K99/R00 awards to begin independent academic laboratories, as well as team-leader positions in leading pharmaceutical companies.
Work Performed
DEFINITION:
The Postdoctoral Appointee holds a PhD or equivalent doctorate (e.g., ScD, MD, DVM). Candidates with non-US degrees may be required to provide proof of degree equivalency.
EXPECTATION:
The conscientious discharge of research or scholarship responsibilities, which may include teaching responsibilities for Postdoctoral Associates Conformance to standards of responsible conduct in research. Compliance with good scholarly and research practice. Maintenance of a laboratory notebook and/or other comparable records of research activity, which remains the property of Duke University upon termination. Adherence to University standards regarding use of isotopes, chemicals, infectious agents, animals, human subjects, and the like. Open and timely discussion with the mentor regarding all facets of the Postdoctoral Appointee's research activities. Postdoctoral Appointees are encouraged to consult the AAMC Compact Between Postdoctoral Appointees and Their Mentors for suggested guidelines for the Postdoctoral Appointee-mentor relationship. Prompt disclosure to the mentor regarding the possession and desire to distribute materials, reagents, software, copyright able and potentially patentable discoveries derived from the Postdoctoral Appointee's research. Collegial conduct towards members of the research group and others as described in the Duke University School of Medicine Honor Code of Professional Conduct and other relevant conduct policies pertaining to other schools at Duke University. Compliance with all applicable University and departmental policies and procedures.
Knowledge, Skills, and Abilities
Some expertise in tissue culture and sterile technique, basic molecular biology skills like PCR, plasmid handling, and protein purification.
Minimum Qualifications
Education
The candidate should hold a PhD degree in biology, neurobiology, or biomedical sciences,
Experience
The candidate should possess a broad basic understanding of neuroscience and neurodegeneration disease research. Good English communication skills, both oral and written, are required.
Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.
Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.
Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.
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