POSTDOCTORAL ASSOCIATE

Updated: 7 months ago
Location: Durham, NORTH CAROLINA
Deadline: The position may have been removed or expired!

School of Medicine:

Established in 1930, Duke University School of Medicine is the youngest of the nation’s top medical schools. Ranked tenth among its peers, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where traditional barriers are low, interdisciplinary collaboration is embraced, and great ideas accelerate translation of fundamental scientific discoveries to improve humanhealth locally and around the globe.

Comprised of 2,400 faculty physicians and researchers, the Duke University School of Medicine along with the Duke University School of Nursing and Duke University Health System create Duke Health. Duke Health is a world-class health care network. Founded in 1998 to provide efficient, responsive care, the health system offers a full network of health services and encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Private Diagnostic Clinic, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.

Post-Doctoral Fellow/Research Associate

Job Description:

The Landstrom Lab is accepting applications for an immediately available, full-time position with the lab for either a Post-Doctoral Research Fellow or Research Associate as a cellular electrophysiologist.   This position is responsible for independently conducting electrophysiology experiments, primarily patch clamp-based, on mammalian cell lines, including mouse primary cardiac myocytes and induced pluripotent stem cell-derived cardiac myocytes (iPSC-CMs), with indirect supervision.  Experience culturing and conducting electrophysiological experiments on immortalized mammalian cell lines (such as HEK293 cells) and isolating mouse primary cardiac myocytes using Langendorff perfusion is required.  Individuals with previous experience with iPSC-CMs are strongly encouraged to apply.  Successful applicants will be assigned to a dedicated patch clamp apparatus complete with data analysis equipment and software.

Required Experience and Skills:

  • PhD, or equivalent experience, in cellular electrophysiology 
  • Independently perform cellular electrophysiology experiments, including patch clamp experiments
  • Independently work with mammalian cell lines and primary cells
  • Willingness to work with non-embryonic human stem cells, mice, and patient blood samples
  • Keep accurate records
  • Strong communication skills
  • Ability to work in a multi-disciplinary team of clinicians, scientists, and trainees 
  • Experience with Microsoft Office, NIH image J, EndNote

Preferred Experience and Skills:

  • Previous experience with electrophysiology studies on cardiac myocytes
  • Previous experience with mouse primary ventricular cardiac myocytes
  • Previous experience with induced pluripotent stem cell-derived cardiac myocytes

Required Experience and Skills:

Education

Doctorate degree with experience in molecular biology and cell physiology

Experience

  • Independently perform iPSC cell culture
  • Independently differentiate and maintain iPSC-CMs
  • Willingness to work with non-embryonic human stem cells, mice, and patient blood samples
  • Keep accurate records
  • Strong communication skills
  • Experience with Microsoft Office, NIH image J, EndNote

Preferred Experience and Skills:

Previous experience with live cell imaging and confocal microscopy

Previous experience with RNA sequencing analysis

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Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.



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