Post Doctoral Research Associate - Marconett Lab

Postdoctoral Research Associate

A position is immediately available (Anticipated start date 8/1/2022) for a postdoctoral research associate in the laboratory of Dr.Crystal Marconett, in the Department of Translational Genomics at the Keck School of Medicine, part of the University of Southern California.  Our research group is investigating the cellular origins of lung cancer, the leading cause of cancer-related death. Specific focus is on understanding which distal cell populations give rise to adenocarcinoma, the largest subtype of lung cancer that disproportionately affects non-smokers and women. We use a combination of bioinformatic and biochemical, molecular and genetic manipulation methods, as well as cell-based and genetically modified mouse models to answer fundamental questions about tumor evolution. Additional details about the lab can be found at: https://sites.google.com/view/marconettlab

The title of the position will be determined by the qualifications and research experience of the candidate and in discussion with the Department. The position is supported by a Hastings Center for Pulmonary Research Postdoctoral Fellowship and is a fixed-term, one-year position with renewal based on productivity. The candidate must have a doctorate degree at the time of employment. The candidate will have active mentoring opportunities as well as opportunities to participate in workshops and conferences relating to the research topic.

Candidates with the following qualifications are encouraged to apply:

Minimum Qualifications

Highly motivated individuals with a Ph.D. or equivalent degree in biology, biochemistry, molecular & cell biology, developmental biology, and/or related disciplines. Previous experience in mammalian cell culture, transfection, recombinant DNA techniques (cloning, PCR), and/or related techniques. Basic molecular and cell biology methods such as immunoprecipitation, western blot, FACS, immunofluorescence/microscopy, and/or related techniques. Candidates have demonstrated ability to complete a project as evidenced by first author publication(s) in nationally/internationally reputed journals in the fields of biochemistry, cell and molecular biology, or related disciplines. Excellent writing and oral communication skills. Knowledge of and a willingness to work with mouse models of lung cancer.

Preferred Qualifications

Experience working with genetically modified murine models, spatiotemporal inactivation of genes and/or lineage tracing. Epigenomic experience (ChIP/ATAC/DNA methylation/etc) is a plus. Bioinformatics experience; such as high dimensional data analysis of public datasets (eg; TCGA) and/or prior analysis of RNA-Seq / ATAC-seq / ChIP-seq / scRNAseq / Multimodal etc is a plus.

Responsibilities:

To work closely with Dr. Marconett, with other members in their group, the Department of Translational Genomics, and with collaborators across multiple institutions working on research questions related to alveolar biology and distal lung diseases, including cancer.To give substantial input in the nature and the direction of the ongoing research projects within the lab and will be encouraged to explore projects that broadly fit within the lab’s research interest To perform research in the relevant discipline area using the appropriate methods and/or techniques To produce research reports and/or publications as required by the funding body or for dissemination to the wider academic community To collaborate with research colleagues and support staff internally as appropriate to the research and to actively develop appropriate external contacts and networks relevant to the project and to future funding opportunities To provide guidance and support to any students associated with the project To attend, contribute, and where necessary lead relevant meetings To take responsibility for planning and developing research methods and techniques within the framework of the research program

The University of Southern California (USC), founded in 1880, is located in the heart of downtown L.A. and is the largest private employer in the City of Los Angeles. As an employee of USC, you will be a part of a world-class research university and a member of the "Trojan Family," which is comprised of the faculty, students and staff that make the university what it is.The university also offers excellent postdoctoral benefits which include: health, dental, vision and life insurance; tuition assistance, disability and retirement plans; credit union membership; and participation in cultural and social events, as well as access to athletic and recreational facilities.

To apply, interested candidates should email [email protected] and include curriculum vitae and a cover letter that describes research interests, motivation(s) for the postdoctoral position and future career plans.

Minimum Education: PhD, MD or equivalent doctorate within previous five years Minimum Experience: 1 year Minimum Field of Expertise: Directly related education in research specialization with advanced knowledge of equipment, procedures and analysis methods