Post doctoral fellow

Department:
SOM KC Cancer Biology

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Washburn
Position Title:
Post doctoral fellow
Job Family Group:
Professional Staff
Job Description Summary:
The Department of Cancer Biology at the University of Kansas Medical Center is seeking a highly motivated candidate to work in the laboratory of Dr. Michael Washburn as a postdoctoral trainee in the field of Quantitative Proteomic Analysis of Human Chromatin Remodeling. The Washburn lab investigates how human chromatin remodeling complexes and protein interaction networks are assembled and function in normal and diseased states. The project involves using the labs molecular, biochemical, and cellular capabilities in addition to recently installed state of the art mass spectrometry systems including a ThermoFisher Scientific Orbitrap Ascend Tribrid with FAIMS and a Bruker Corporation timsTOF HT with quantitative proteomic and metabolomic capabilities. The successful candidate is expected to perform research by contributing to the design of experiments, data acquisition, data analysis and interpretation, manuscript preparation, and mentor junior researchers.
Job Description:
Required Qualifications

Education: PhD in biochemistry, chemistry, molecular biology, structural biology or related field.

Preferred Qualifications

Experience:

• Experience in biochemical, molecular, structural, and/or cellular biology related techniques.

• Experience in human cell and tissue culture, protein purification techniques, and other molecular biology techniques.

• Experience in protein mass spectrometry is not required but is a major plus.

• Research experience and familiarity with standard biochemical techniques.

Skills:

• Excellent organizational skills and time management skills.

• Ability to work independently and as a team.

• Track record of publications.

• Excellent interpersonal, verbal and written communication skills.

Job Duties Outlined

• Research Overview: Work with PI/faculty mentor and other laboratory members, to design and perform experiments studying how human chromatin remodeling complexes are assembled and how they function in normal and diseased states.  While a major focus will be to use state of the art mass spectrometry technologies to carry out these studies, other methods like biochemical assays, ChIP-Seq, microscopy and possibly CryoEM will be used to study the structure and function of these complexes.  The lab is equipped with tissue culture facilities, biochemical, and molecular capabilities to carry out these duties.  In addition, there are state of the art proteomic and metabolomic mass spectrometry technologies, in addition to CryoEM technologies to further drive these studies.  Lastly, given the highly collaborative nature of the laboratory there will be opportunities to collaborate with and participate in disease-based projects (cancer, neurological, pulmonary, metabolic, etc.).  The laboratory has many active and emerging projects applying these methods to human health and disease.   

• Interpretation of experimental results and analysis of data, to use in publications, grants and determining next steps in the needed for the research.

• Perform experiments requiring the flexibility and adaptability to execute a wide range of skills to perform a variety of bench experiments and utilize the labs equipment. This includes but not limited to working with human cell and tissue culture and standard biochemical and molecular biology techniques.

• Prepare samples for analysis by state-of-the-art mass spectrometry systems and interpret the resulting datasets using computational tools like ProteomeDiscoverer, xiVIew, Cytoscape, and other computational tools.

• Postdoc Expectations: The Postdoc will be expected to complete research projects under the guidance of the faculty mentor, record and interpret the results of their experiments in an (electronic) laboratory notebook, prepare publication-quality manuscripts (including figures and tables) and publish in peer-reviewed literature.

• Read literature articles, develop new ideas, and assimilate the information into his/her project design/interpretation.

• Dissemination of studies: Interact on a regular basis with their faculty mentor and members of the laboratory to discuss experimental design and interpretation of results.

• Present research aims and findings at department seminars and at scientific meetings. Write and publish their results as first author in abstracts, manuscripts, and posters.

• Submit fellowship applications, as eligible, to bolster research funding and CV building for projects.

• Interact with KU Cancer Center donors and local cancer affiliates.

• Compliance: Attend and maintain compliance on all orientation and training sessions designated by the University and the Cancer Biology Department, understand and follow IACUC and biosafety protocols, and attend departmental seminars and regular lab meetings.

• Perform other duties assigned by PI and faculty mentor.

Required Documents:

• Resume/CV

• Cover Letter

Comprehensive Benefits Package:

Coverage begins on day one for health, dental, and vision insurance and includes health expense accounts with generous employer contributions if the employee participates in a qualifying health plan. Employer-paid life insurance, long-term disability insurance, and various additional voluntary insurance plans are available. Paid time off, including vacation and sick, begins accruing upon hire, plus nine paid holidays. One paid discretionary day is available after six months of employment, and paid time off for bereavement, jury duty, military service, and parental leave is available after 12 months of employment. A retirement program with a generous employer contribution and additional voluntary retirement programs (457 or 403b) are available. https://www.kumc.edu/human-resources/benefits.html

Employee Type:
Regular
Time Type:
Full time
Rate Type:
Salary

Compensation Statement:

The pay range listed for this position is determined by our compensation program using market data and salary benchmarking. A combination of factors is considered in making compensation decisions including, but not limited to, education, experience and training, qualifications relative to the requirements of the position, and funding. At the University of Kansas Medical Center, a reasonable estimate for the starting pay range will be the minimum to midpoint of the posted range, taking into account the combination of factors listed above. 

Pay Range:
$47,476.00 - $80,000.00

Minimum

$47,476.00

Midpoint

$66,000.00

Maximum

$80,000.00