Post-Doc Research Associate

Updated: 16 days ago
Location: Chapel Hill, NORTH CAROLINA
Job Type: FullTime
Deadline: ; ;

Posting Information
Posting Details

Department Lineberger Compr Cancer Center - 426801
Posting Open Date 06/09/2022
Application Deadline
Open Until Filled No
Position Type Postdoctoral Scholar
Position Title Post-Doc Research Associate
Vacancy ID PDS003488
Full-time/Part-time Full-Time Temporary
Hours per week 40
Work Location Chapel Hill, NC
Position Location North Carolina, US
Hiring Range Commensurate with experience
Proposed Start Date 06/20/2022
Estimated Duration of Appointment 12 Months

Position Information

Primary Purpose of Organizational Unit
The UNC School of Medicine has a rich tradition of excellence and care. Our mission is to improve the health and wellbeing of North Carolinians, and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research. We strive to promote faculty, staff, and learner development in a diverse, respectful environment where our colleagues demonstrate professionalism, enhance learning, and create personal and professional sustainability. We optimize our partnership with the UNC Health System through close collaboration and commitment to service.
Our vision is to be the nation’s leading public school of medicine. We are ranked 2nd in primary care education among all US schools of medicine and 5th among public peers in NIH research funding. Our Allied Health Department is home to five top-ranked divisions, and we are home to 18 top-ranked clinical and basic science departments in NIH research funding.
Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research.
Patient Care: We will promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond.
Education: We will prepare tomorrow’s health care professionals and biomedical researchers by facilitating learning within innovative curricula and team-oriented interprofessional education. We will cultivate outstanding teaching and research faculty, and we will recruit outstanding students and trainees from highly diverse backgrounds to create a socially responsible, highly skilled workforce.
Research: We will develop and support a rich array of outstanding health sciences research programs, centers, and resources. We will provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our University to support outstanding research. We will foster programs in the areas of basic, translational, mechanistic, and population research.
Position Summary
A postdoctoral research associate position is available to conduct breast cancer research and dissecting DNA damage and immunotherapy responses.
We are seeking highly motivated and collaborative postdoctoral researcher to join the Gupta lab at the University of North Carolina in Chapel Hill to lead funded research projects at the nexus between DNA damage responses and breast tumor immunology. You will join a diverse and dynamic research group that studies mechanisms of DNA repair, DNA damage responses, tumor immunology, and breast cancer biology. Our lab employs sophisticated in vitro and in vivo models of triple negative breast cancer and CRISPR engineering to assess DNA repair, DNA damage responses, and/or immune sensing pathways and evaluate their effects on therapeutic response. In particular, we are interested in DNA polymerase theta as an emerging therapeutic target in breast cancer. Additionally, we are investigating the role of DNA damage and immune sensing pathways in determining response to radiation and immunotherapy combinations. The projects will use a variety of advanced molecular assays including CRISPR screening, single cell RNAseq, and/or spatial transcriptomics to evaluate the phenotypic consequences of genetic perturbations. The projects will also have a translational component with access to patient specimens from a clinical trial of immunotherapy and radiation in breast cancer. This is a unique opportunity to join a great lab group and work on an exciting scientific project that may also be clinically impactful.
Minimum Education and Experience Requirements
The applicant must have a MD or PhD in molecular and cellular biology, biochemistry or related degree.
Required Qualifications, Competencies, and Experience
The applicant must have a MD or PhD in molecular and cellular biology, biochemistry or related degree.
Preferred Qualifications, Competencies, and Experience
Prior experience in molecular biology, cancer biology and/or tumor immunology is preferred, as is a willingness to learn bioinformatics methods.
Special Physical/Mental Requirements
Special Instructions
For information on UNC Postdoctoral Benefits and Services click here
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Posting Contact Information

Department Contact Name and Title Rhiannon Wagoner, HR Consultant
Department Contact Telephone or Email
Postdoctoral Affairs Contact Information

If you experience any problems accessing the system or have questions about the application process, please contact the University’s Equal Employment Opportunity office at (919) 966-3576 or send an email to

Please note: The Equal Employment Opportunity office will not be able to provide specific updates regarding position or application status.

Equal Opportunity Employer Statement
The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran.

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