Post-Doc Research Associate

University of North Carolina at Chapel Hill, United States

Updated: 11 days ago
Location: Chapel Hill, NORTH CAROLINA
Job Type: FullTime
Deadline: 19 Apr 2024

Posting Information
Posting Details


Department Med-UNC Blood Research Center - 411494
Posting Open Date 04/09/2024
Application Deadline 04/19/2024
Open Until Filled No
Position Type Postdoctoral Scholar
Position Title Post-Doc Research Associate
Vacancy ID PDS004164
Full-time/Part-time Full-Time Temporary
Hours per week 40
FTE 1
Work Location Chapel Hill, NC
Position Location North Carolina, US
Hiring Range $48,500 - $52,000
Proposed Start Date 09/01/2024
Estimated Duration of Appointment 12 Months

Position Information


Be a Tar Heel!
A global higher education leader in innovative teaching, research and public service, the University of North Carolina at Chapel Hill consistently ranks as one of the nation’s top public universities and is among is the top ten research universities in the nation for federal research expenditures as well as for federally funded social and behavioral sciences research and development.
Here at Carolina, our highly skilled postdocs play a vital role in our research enterprise and towards our overall commitment to research excellence. Across many disciplines, postdocs contribute to the intellectual vitality of the University. They provide innovative ideas and perspectives, foster a stimulating research environment and advance knowledge within their fields. Postdocs are crucial members of our scientific research workforce, contributors to our research outputs and an important reason why Carolina is one of the leading public research institutions in the country.
UNC-Chapel Hill offers postdocs comprehensive medical and vision coverage , paid leave, and benefits and services that support professional development and a healthy work/life balance. Chapel Hill regularly ranks as one of the best college towns and best places to live in the United States, a reputation guided by the diverse social, cultural, recreation and professional opportunities that span the campus and community.
Primary Purpose of Organizational Unit
The UNC School of Medicine has a rich tradition of excellence and care. Our mission is to improve the health and wellbeing of North Carolinians, and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research. We strive to promote faculty, staff, and learner development in a diverse, respectful environment where our colleagues demonstrate professionalism, enhance learning, and create personal and professional sustainability. We optimize our partnership with the UNC Health System through close collaboration and commitment to service.
OUR VISION
Our vision is to be the nation’s leading public school of medicine. We are ranked 2nd in primary care education among all US schools of medicine and 5th among public peers in NIH research funding. Our Allied Health Department is home to five top-ranked divisions, and we are home to 18 top-ranked clinical and basic science departments in NIH research funding.
OUR MISSION
Our mission is to improve the health and well-being of North Carolinians and others whom we serve. We accomplish this by providing leadership and excellence in the interrelated areas of patient care, education, and research.
Patient Care: We will promote health and provide superb clinical care while maintaining our strong tradition of reaching underserved populations and reducing health disparities across North Carolina and beyond.
Education: We will prepare tomorrow’s health care professionals and biomedical researchers by facilitating learning within innovative curricula and team-oriented interprofessional education. We will cultivate outstanding teaching and research faculty, and we will recruit outstanding students and trainees from highly diverse backgrounds to create a socially responsible, highly skilled workforce.
Research: We will develop and support a rich array of outstanding health sciences research programs, centers, and resources. We will provide infrastructure and opportunities for collaboration among disciplines throughout and beyond our University to support outstanding research. We will foster programs in the areas of basic, translational, mechanistic, and population research.
Position Summary
A Postdoctoral Research Associate A postdoctoral research position is available at the UNC Blood Research Center. The Blood Research Center is a nexus of interdisciplinary research of non-malignant blood disorders across UNC. Our current research spans cellular and non-cellular factors that impact hemostasis and thrombosis, including crosstalk between coagulation and inflammation in different cardiovascular and hematologic disorders.
Our research focuses on translational research, taking clinical observations to the laboratory to gain better insight into disease pathogenesis and potential treatments for Sickle Cell Disease and Myeloproliferative Neoplasms (MPN).
The laboratory offers three ongoing projects:
Investigating the contribution and the mechanism by which activation of contact pathway contributes to the thrombo-inflammatory complications associated with sickle cell disease. The study will involve using a humanized mouse model of sickle cell disease as well as clinical samples obtained from sickle cell disease patients.
Investigating the mechanisms of venous thrombosis and chronic kidney disease in Sickle Cell Trait. By dissecting the role of RBC sickling in the harsh biophysical environments observed in venous thrombi and in the renal medulla, we expect to identify potential strategies to prevent the related clinical complications.
Investigating the qualitative cellular changes in MPN that lead to increased thrombotic risk, using both patient samples and mouse models. A JAK2 V617F mouse model of MPN will be used to evaluate pathogenesis of increased thrombosis. Human MPN samples will be collected and banked for single cell RNA sequencing and studies of coagulation potential to identify biomarkers of increased thrombotic risk and how current MPN-directed therapies affect those pathways.
Minimum Education and Experience Requirements
MD and/or PhD in Biology or Pathology, or a closely related discipline. The candidate should have at least two first author publications.PhD in Biology, Pathology, Pharmacology, Toxicology, Immunology or a related discipline.
Required Qualifications, Competencies, and Experience
Animal handling and basic surgical skill experience.
Preferred Qualifications, Competencies, and Experience
A strong background in molecular biology and pathology, with an emphasis in immunothrombosis is also preferred. Experience with assays such as western blot, flow cytometry, dynamic light scattering, ELISA, enzyme kinetics, confocal microscopy, real-time quantitative PCR is essential. Familiarity with handling of human blood, or blood products is preferred. Experience in performing clinical blood coagulation assays and mouse models of venous thrombosis is a plus.
Special Physical/Mental Requirements
Special Instructions
For information on UNC Postdoctoral Benefits and Services click here
Quick Link https://unc.peopleadmin.com/postings/278008

Posting Contact Information


Department Contact Name and Title Shelby Abbott-Lunsford, HR Consultant
Department Contact Telephone or Email [email protected]
Postdoctoral Affairs Contact Information
If you experience any problems accessing the system or have questions about the application process, please contact the University’s Office of Postdoctoral Affairs at (919) 962-9982 or send an email to [email protected] .
Please note: The Office of Postdoctoral Affairs will not be able to provide specific updates regarding position or application status.
Equal Opportunity Employer Statement
The University of North Carolina at Chapel Hill is an equal opportunity and affirmative action employer. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender, gender expression, gender identity, genetic information, race, national origin, religion, sex, sexual orientation, or status as a protected veteran.

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