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towards the development of safe and effective vaccines against HIV-1, malaria and other pathogens. Our major emphasis is the design of protein immunogens and understanding the immune response following
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The successful candidate will be expected to: Perform and assist with experiments involving recombinant DNA technology, immunology, and general molecular biology techniques, including the use of using animal
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laboratory aims to understand the immunology of HIV-1 antibodies and the molecular biology of their interaction with HIV-1 envelope (Env) glycoprotein. Our overall goal is to develop protective antibody-based
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successful applicant to analyze rhesus Env-Ab coevolution leading to bNAbs targeting V2 apex, V3 glycan, CD4bs and fusion peptide epitopes as a molecular guide for HIV-1 immunogen design in humans. Work will
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. Annual research funding in immunology and infectious diseases exceeds $100M across CWRU and affiliates. The Pathology Department is ranked in the top 10-13 nationally for NIH funding. Other assets include
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. As a professor of molecular virology at the Erasmus University Medical Centre, Fouchier studies how viruses evolve and can become pathogenic, switch hosts, become airborne, and escape the host’s immune
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other kinetoplastid pathogens of man and livestock, although due to its small genome size (9.5 Mb, <5,500 genes), it has reduced metabolic capacity [6]. Furthermore, while molecular data indicates