LABORATORY RESEARCH ANALYST II

School of Medicine

Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,600 faculty physicians and researchers, nearly 2,000 students, and more than 6,200 staff, the Duke University School of Medicine along with the Duke University School of Nursing, and Duke University Health System comprise Duke Health, a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Health Integrated Practice, Duke Primary Care, Duke Home Care and Hospice, Duke Health and Wellness, and multiple affiliations.

Occupational Summary: 

Conduct a variety of complex and independent investigations in the planning, development and implementation of original experimental procedures within the overall scope of a research project at Duke University. 

Position Description: 

The Graves laboratory within the Department of Pediatrics is a translational research lab focused on the biology of drug resistance and progression in osteosarcoma. We are seeking an experienced research analyst to take a leadership role within the lab on projects utilizing pre-clinical models (including patient-derived organoids, pulmonary metastasis assays, and in vivo mouse xenografts) in the study of chemotherapy-resistant osteosarcoma 

The research analyst will work under the direct supervision of Dr. Laurie Graves and will be expected to carry out research related to actively and prospectively funded projects, including collaborating with other laboratory researchers, clinical research team members, bioinformaticians, and biostatisticians. The candidate will need to independently develop experiments, analyze and interpret data, and document all research activities and data for subsequent use in publications and grant applications. 

This position will be supported for two years with the potential for extension based on funding. The ideal candidate will have: 

• Experience working with mammalian cell culture, patient-derived models (organoids, cell lines) and mouse models of cancer (xenografts) 

• Experience performing western blotting, RNA/DNA extractions, qRT-PCR, and genomics-based analysis of cancer cell lines, including gene expression profiling and next-generation sequencing 

• Familiarity with bioinformatic and biostatistical approaches for the analysis of sequencing and proteomic data 

• Desire to conduct team-based science in close collaboration with clinicians, statisticians, and regulators 

• Excellent verbal and written English communication skills with outstanding organizational and analytical abilities 

Interested candidates should send CVs to Dr. Laurie Graves ([email protected]) for consideration. Select candidates will undergo a virtual interview and finalists will be interviewed in-person at Duke University. 

Required Qualifications at this Level 

Education/Training 

Work requires a bachelor's degree in botany, biology, zoology, psychology or other directly related scientific field. 

Experience 

Work requires four years of research experience. A related master's degree may offset required years of experience on a 1:1 basis, e.g., a two year master's degree in lieu of two years of experience. 

OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE 

Skills 

N/A

Work requires a bachelor's degree in botany, biology, zoology, psychology or other directly related scientific field.

Work requires four years of research experience. A related master's OR AN EQUIVALENT COMBINATION OF RELEVANT EDUCATION AND/OR EXPERIENCE degree may offset required years of experience on a 1:1 basis, e.g., a two year master's degree in lieu of two years of experience.

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.