Laboratory Manager - Littman Lab

Updated: about 8 hours ago
Location: New York City, NEW YORK
Job Type: FullTime

Primary Work Address: NYU Medical Center, New York, NY, 10016-6481


Current HHMI Employees, click here to apply via your Workday account.

We are currently looking for an enthusiastic, proactive and dedicated Laboratory Manager to manage the day-to-day operations supporting the research of Dr. Dan Littman’s group at New York University School of Medicine.  The Littman lab investigates how T lymphocytes acquire functional properties during development and in response to distinct intestinal microbiota that influence systemic inflammatory processes (e.g. T cell-mediated autoimmune diseases, cancer, and responses to infection with HIV and other pathogenic microbes). We also study how the immune system and the microbiota interact with the enteric and central nervous systems at homeostasis and under pathological conditions.  More information on the lab can be found on our website: https://www.littmanlab.org

The ideal candidate will be someone with a strong background in the sciences who is passionate about furthering the lab’s understanding in the areas of immunology, microbiome, neuroimmunology, single cell genomics, transcriptional regulation, and mouse genetics, and is self-driven, creative, and willing to tackle novel challenges.  This individual will be excited to become an integral and leading member of the Littman lab, to help orient and train new lab members, supervise management of a large mouse colony, and to serve as a key liaison between the lab, NYU departments, HHMI, and external stakeholders.  Based on the chosen candidate’s career interests and capabilities, there may be opportunity to conduct an independent research project, attend conferences, and contribute to publications.

Principal Responsibilities:

  • Supervise and manage (with research technicians) efficient use of a large mouse colony by students and postdoctoral fellows. This will include mouse genotyping, breeding, and embryo/sperm freezing programs, in the most cost-effective manner.

  • Supervise management of the plasmid and cell line inventories.

  • Manage the budget and spending oversight for the lab, determine supply needs, place orders, negotiate with vendors, perform cost analysis of research projects.

  • Oversee equipment maintenance, inventory, and repair.

  • Ensure lab compliance in all applicable safety programs, IACUC and other relevant protocols, regulations, and computer software licenses and updates.

  • Ensure the lab’s proper use of Benchling electronic notebook and lab management software.

  • Train graduate students and technicians in a variety of laboratory procedures as needed.

  • Supervise technicians and assist with time management among lab members to maintain organization and smooth running of the lab.

  • Assign shared responsibilities (including several listed above) to lab members.

Qualifications:

  • A bachelor’s degree in the biological sciences is required. An advanced degree (master’s, PhD, etc.) would be a plus.

  • A minimum of 3-5 years of hands-on wet laboratory research experience:

    • Experience in molecular biology (e.g. RNAseq, molecular cloning, library construction, PCR, recombinant protein expression and purification) and mammalian cell culture (e.g. transfections, retroviral transductions, reporter assays) is required.

    • Experience in mouse genetics (mouse breeding, genotyping, phenotyping by immunohistochemistry and FACS screening) is strongly preferred.

    • Experience with mouse colony management is strongly preferred.

    • Experience in laboratory management would be a significant plus.

  • Comfortable working with live mice on a daily basis.

  • Strong initiative, self-motivation, and capacity for creative problem solving.

  • Excellent interpersonal as well as verbal and written communication skills.

  • Meticulous attention to detail with a high degree of accuracy and skill in organization, prioritization, and time management.

  • General proficiency in Microsoft Office Suite (Word, Excel, Outlook) is required. Familiarity with Benchling would be a plus.

  • Ability to train research technicians and graduate students on scientific techniques as needed.

  • Ability to work well both independently and as a member of a team, with a wide variety of people from diverse backgrounds, to meet deadlines efficiently while being adaptable to changing priorities.

Physical Requirements:

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances.

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

Please Note:

This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however.  Unless they begin with the word “may,” the Essential Duties and Responsibilities described above are “essential functions” of the job, as defined by the Americans with Disabilities Act.


HHMI is an Equal Opportunity Employer

Primary Work Address: NYU Medical Center, New York, NY, 10016-6481


Current HHMI Employees, click here to apply via your Workday account.

We are currently looking for an enthusiastic, proactive and dedicated Laboratory Manager to manage the day-to-day operations supporting the research of Dr. Dan Littman’s group at New York University School of Medicine.  The Littman lab investigates how T lymphocytes acquire functional properties during development and in response to distinct intestinal microbiota that influence systemic inflammatory processes (e.g. T cell-mediated autoimmune diseases, cancer, and responses to infection with HIV and other pathogenic microbes). We also study how the immune system and the microbiota interact with the enteric and central nervous systems at homeostasis and under pathological conditions.  More information on the lab can be found on our website: https://www.littmanlab.org

The ideal candidate will be someone with a strong background in the sciences who is passionate about furthering the lab’s understanding in the areas of immunology, microbiome, neuroimmunology, single cell genomics, transcriptional regulation, and mouse genetics, and is self-driven, creative, and willing to tackle novel challenges.  This individual will be excited to become an integral and leading member of the Littman lab, to help orient and train new lab members, supervise management of a large mouse colony, and to serve as a key liaison between the lab, NYU departments, HHMI, and external stakeholders.  Based on the chosen candidate’s career interests and capabilities, there may be opportunity to conduct an independent research project, attend conferences, and contribute to publications.

Principal Responsibilities:

  • Supervise and manage (with research technicians) efficient use of a large mouse colony by students and postdoctoral fellows. This will include mouse genotyping, breeding, and embryo/sperm freezing programs, in the most cost-effective manner.

  • Supervise management of the plasmid and cell line inventories.

  • Manage the budget and spending oversight for the lab, determine supply needs, place orders, negotiate with vendors, perform cost analysis of research projects.

  • Oversee equipment maintenance, inventory, and repair.

  • Ensure lab compliance in all applicable safety programs, IACUC and other relevant protocols, regulations, and computer software licenses and updates.

  • Ensure the lab’s proper use of Benchling electronic notebook and lab management software.

  • Train graduate students and technicians in a variety of laboratory procedures as needed.

  • Supervise technicians and assist with time management among lab members to maintain organization and smooth running of the lab.

  • Assign shared responsibilities (including several listed above) to lab members.

Qualifications:

  • A bachelor’s degree in the biological sciences is required. An advanced degree (master’s, PhD, etc.) would be a plus.

  • A minimum of 3-5 years of hands-on wet laboratory research experience:

    • Experience in molecular biology (e.g. RNAseq, molecular cloning, library construction, PCR, recombinant protein expression and purification) and mammalian cell culture (e.g. transfections, retroviral transductions, reporter assays) is required.

    • Experience in mouse genetics (mouse breeding, genotyping, phenotyping by immunohistochemistry and FACS screening) is strongly preferred.

    • Experience with mouse colony management is strongly preferred.

    • Experience in laboratory management would be a significant plus.

  • Comfortable working with live mice on a daily basis.

  • Strong initiative, self-motivation, and capacity for creative problem solving.

  • Excellent interpersonal as well as verbal and written communication skills.

  • Meticulous attention to detail with a high degree of accuracy and skill in organization, prioritization, and time management.

  • General proficiency in Microsoft Office Suite (Word, Excel, Outlook) is required. Familiarity with Benchling would be a plus.

  • Ability to train research technicians and graduate students on scientific techniques as needed.

  • Ability to work well both independently and as a member of a team, with a wide variety of people from diverse backgrounds, to meet deadlines efficiently while being adaptable to changing priorities.

Physical Requirements:

Remaining in a normal seated or standing position for extended periods of time; reaching and grasping by extending hand(s) or arm(s); dexterity to manipulate objects with fingers, for example using a keyboard; communication skills using the spoken word; ability to see and hear within normal parameters; ability to move about workspace. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). Work may involve possible exposure to malodorous vapors, low dose radiation, contamination by toxic chemicals and acids and presence of carcinogenic substances.

Persons with disabilities may be able to perform the essential duties of this position with reasonable accommodation. Requests for reasonable accommodation will be evaluated on an individual basis.

Please Note:

This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however.  Unless they begin with the word “may,” the Essential Duties and Responsibilities described above are “essential functions” of the job, as defined by the Americans with Disabilities Act.


HHMI is an Equal Opportunity Employer

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