Lab Manager

The Department of Anesthesiology and Critical Care Medicine at Johns Hopkins University is seeking a Laboratory Manager to manage a large animal laboratory. The laboratory is made up of multiple Principal Investigators, and the central theme of the research is on how abnormal perinatal and pediatric physiological states impact brain function and brain development in multi-disciplinary projects in multiple species. We perform state-of-the-art and innovative experiments using a preclinical pediatric swine model to study cardiac arrest, brain injury mechanisms, and potential treatments to improve neurologic outcomes in children after brain injury. In addition, we evaluate how different classes of anesthetics commonly used in children affect cerebrovascular function in different pathophysiologic states, including stroke. Our primary preclinical models are neonatal and infant piglets, neonatal rats, adult rats, and rabbits. We are developing new medical devices to non-invasively assess the oxygenation of the brain in the fetus and newborn by validating the technology in pregnant sheep and newborn piglet models of hypoxia and stroke. We are developing nanomedicine technologies to prevent cerebral palsy arising from intrauterine inflammation in a pregnant rabbit model. Our work is supported by various funding sources including the NIH and the American Heart Association. An ideal candidate will have prior experience in an academic, large animal laboratory. Responsibilities will include assisting with surgery and experimental protocols, scheduling experiments, performing daily animal care, collaborating with our veterinary colleagues, maintaining and troubleshooting lab equipment, ordering supplies, overseeing site visits by regulatory bodies, analyzing data, performing basic bench protocols, and participating in weekly laboratory meetings.

Specific Duties & Responsibilities

• The manager will conduct all laboratory activities on animals in compliance with our Animal Care and Use Committee approved protocols and safety protocols.
• Specific job duties include,

• Humane care for animals includes receiving, feeding, daily care, and post-operative monitoring.
• Assist with experimental preparation and protocols including anesthetizing animals, performing surgeries such as arterial and venous access, intubation or tracheostomy, intracranial pressure monitoring, administering medications, obtaining blood samples, performing detailed hemodynamic intervention protocols.
• Collaborate with our veterinary colleagues to ensure humane care of animals.
• Contribute intellectually to the design of diverse physiological experiments. Work with principal investigators in developing and implementing surgical animal models for complex physiological experiments and provide advice on how to refine experimental procedures related to studies on animals.
• Euthanize animals and process tissues at experimental end points.
• Maintain lab equipment and coordinate repairs for 4 large animal surgical stations.
• Maintain lab area and clean labware.
• Assure that handling of drugs and pain medications are in accordance with regulations and that staff accurately keeps inventory logs.
• Oversee site visits by animal welfare and biosafety regulatory bodies.
• Manage supply inventory and coordinate ordering of supplies and shipping of animals.
• Train other technicians, research fellows, residents and students in surgical techniques related to experimental protocols and basic laboratory procedures. Ensure quality assurance in the performance of surgical techniques.
• Perform data entry and ensure complete and accurate database management. Communicate with and assist the principal investigators in reviewing study data, performing data analyses, basic statistical operations, and creating graphs.
• Preparing laboratory reagents necessary for tissue processing.
• Attending weekly lab meetings and giving oral updates on work.
• Attending courses in safety procedures for handling, storage and disposal of biohazardous materials.
• May also include performing basic science techniques, such as ELISA assay and immunohistochemistry of tissue.

Minimum Qualifications

• Bachelor's Degree in Biology, Chemistry or related field.
• Five years related experience, including proven technical knowledge and laboratory experience.
• Master's Degree, with related graduate research, may substitute for experience to the extent permitted by the JHU equivalency formula.

Preferred Qualifications

• High level of organizational skills.
• Experience in managing laboratory research projects and supervising personnel.
• Strong analytical background is highly desirable including the ability to diagnose the cause of aberrant data or troubleshoot problems with equipment.
• Knowledge of basic cardiovascular physiology and neuroscience. Experience with standard laboratory practices, animal anesthesia, surgery and postoperative care procedures, and animal care and use regulations.
• Knowledge of biosafety and controlled substance regulations.
• Effective verbal and written communication skills.
• Excellent interpersonal skills with ability to work with multiple faculty members, postdoctoral fellows, and technicians.
• Ability to work on own initiative to achieve specific project goals. Ability to prioritize work and to multi-task.

Classified Title: Laboratory Manager
Job Posting Title (Working Title): Lab Manager
Role/Level/Range: ACRP/04/MD
Starting Salary Range: Min $55,200 - Max $96,600 Annually ($90,000 targeted; Commensurate with experience)
Employee group: Full Time
Schedule: Work days/hours (i.e. Mon-Fri with possible weekend/evening hrs) 7.5 hours/day Mon-Fri with possible evenings and weekends
Exempt Status: Exempt
Location: School of Medicine Campus
Department name: ​​​​​​​SOM Ane Research
Personnel area: School of Medicine 

Total Rewards
The referenced salary range is based on Johns Hopkins University’s good faith belief at the time of posting. Actual compensation may vary based on factors such as geographic location, work experience, market conditions, education/training and skill level. Johns Hopkins offers a total rewards package that supports our employees' health, life, career and retirement. More information can be found here: https://hr.jhu.edu/benefits-worklife/

Please refer to the job description above to see which forms of equivalency are permitted for this position. If permitted, equivalencies will follow these guidelines:
JHU Equivalency Formula: 30 undergraduate degree credits (semester hours) or 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.

**Applicants who do not meet the posted requirements but are completing their final academic semester/quarter will be considered eligible for employment and may be asked to provide additional information confirming their academic completion date.

The successful candidate(s) for this position will be subject to a pre-employment background check. Johns Hopkins is committed to hiring individuals with a justice-involved background, consistent with applicable policies and current practice. A prior criminal history does not automatically preclude candidates from employment at Johns Hopkins University. In accordance with applicable law, the university will review, on an individual basis, the date of a candidate’s conviction, the nature of the conviction and how the conviction relates to an essential job-related qualification or function.

The Johns Hopkins University values diversity, equity and inclusion and advances these through our key strategic framework, the JHU Roadmap on Diversity and Inclusion .

Accommodation Information

If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the Talent Acquisition Office at [email protected] . For TTY users, call via Maryland Relay or dial 711. For more information about workplace accommodations or accessibility at Johns Hopkins University, please visit accessibility.jhu.edu .

Johns Hopkins has mandated COVID-19 and influenza vaccines, as applicable. The COVID-19 vaccine does not apply to positions located in the State of Florida. Exceptions to the COVID and flu vaccine requirements may be provided to individuals for religious beliefs or medical reasons. Requests for an exception must be submitted to the JHU vaccination registry. For additional information, applicants for SOM positions should visit https://www.hopkinsmedicine.org/coronavirus/covid-19-vaccine/ and all other JHU applicants should visit https://covidinfo.jhu.edu/health-safety/covid-vaccination-information/ .

The following additional provisions may apply, depending on campus. Your recruiter will advise accordingly.

The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.

Note: Job Postings are updated daily and remain online until filled.