LAB AST 2 (Laboratory Technician - Morrison Lab)

The California National Primate Research Center, CNPRC at UC Davis, is an Organized Research Unit that conducts interdisciplinary research programs on significant human health problems where non-human primates is the animal of choice. In addition to its major efforts in the area of research, the CNPRC is also committed to both UC Davis and NIH missions of teaching and service.

Job Summary

Under general supervision, perform technical laboratory procedures in support of research activities focused on the characterization of synaptic health in cognitive aging and in neurological disorders in nonhuman primates. Work closely with PI, Lab Manager and laboratory academic personnel by providing technical laboratory support, data entry and analyses of lab data, processing and storing cell and animal tissue samples, and conducting laboratory procedures according to established protocols, and implementing and managing complex behavioral testing procedures related to the projects to ensure consistency and compliance with each specific grant. Perform data collection and data management including, assisting with biochemical and microscopy data collection from samples collected from rhesus monkey.

Collect images and data with confocal microscopy. Perform analyses of dendritic arborization and dendritic spines densities. Perform statistical analysis on quantitative data collected from microscopic techniques. Manage collected data, insuring robust backup systems are in place. Assist in the training/conditioning of animals for preparation of behavioral testing in their testing environments, and perform various cognitive behavioral tests.

POSITION INFORMATION

PHYSICAL DEMANDS

• Laboratory work requires performing repetitive tasks, responding to timers.
• Performing several tests simultaneously, using analytical instruments associated with laboratory work, and using microscopes (and other sensitive lab equipment) for long periods.
• Safely lift and carry objects such as lab tools and biomaterials and chemical (stains, regents, and buffers) up to 30 pounds.
• Lift and access items located above counter level.
• Has direct contact to work with animals.
• Use of biological safety cabinets in use of balance, pH meter, laboratory instruments such as laminar flow hoods, centrifuges, plate washers, ELISA readers, flow cytometers.
• Provide after hour, weekend, and holiday emergency support to ensure projects are attended according to protocols and schedules.
• Perform diversified tasks that may require standing, squatting, kneeling, bending, stooping, or standing up to 8 hours per day.
• Wear protective clothing for extended periods of time including gown, coveralls, gloves, masks, face shields, goggles, sleeves and head covers in according to protocols.

WORK ENVIRONMENT

• This position is a critical position and subject to a background check. Employment is contingent upon successful completion of background investigation including criminal history and identity check.
• Measles vaccination or proof of illness required. This position is subject to Medical Surveillance procedures and review in accordance with Federal and State Laws and Regulations and University Policy.
• Perform assigned duties in BioSafety Level 2+ facilities where non-human primates may be either naturally or experimentally infected with potentially hazardous infectious agents such as SIV or Herpes B virus.
• Wear protective clothing for extended periods of time including: gown, lab coats, gloves, masks, face shield, and head cover.
• Work with human and nonhuman primate specimens and chemical agents. Position may require employee to work with or be in areas where hazardous materials and/or infectious diseases are present. In such instances, employee will be required to wear protective clothing for personal protection from infectious diseases and animals.
• Work irregular hours (early mornings, early evening, and/or weekends, as needed). Work occasional overtime including some weekends and holidays.
• California National Primate Research Center employees are directly or indirectly engaged in the performance of work on Federal or State contracts and grants as well as periodically come into contact with controlled substances; and are expected to abide by the UC Policy on Substance Abuse, the Federal Drug-Free Workplace Act of 1988, and the State Drug-Free Workplace Act of 1990.
• The Smoke and Tobacco Free Environment policy is intended to provide a healthier, safer, and more productive work and learning environment for the entire UC community. The University of California prohibits smoking and tobacco use at all University owned or leased properties, or facilities operated by UC staff or faculty. Smoking and tobacco use are strictly prohibited in indoor and outdoor spaces, parking lots, residential space, and University vehicles. https://ucdavispolicy.ellucid.com/documents/view/271

MINIMUM QUALIFICATIONS

Minimum Education/Experience:           

• Completion of lower division college level coursework in Neuroscience, Molecular Biology, Microbiology, Cell Biology, or Biochemistry with a focus on molecular biology, cell biology, and/or neuroscience theories and principles, or an equivalent combination of education and experience.
• Experience working in a research laboratory performing laboratory procedures in the areas of Neuroscience, Molecular Biology, Microbiology, Cell Biology, and/or Biochemistry, Animal Science, Animal Biology, or related research fields involving animal models (nonhuman primates or rodents) used in research laboratory.
• Experience with computer applications (includes 3-D constructs) for transcribing raw data and entering and analyzing sample/research results.

Minimum Knowledge, Skills, and Abilities (KSA) :

• Skills and knowledge to apply and understand concepts of translational research including working with and handling animals in a research environment (assisting in sterile techniques including tissue harvests, collection of specimens, and other animal-related procedures).
• Applied mathematical skills to calculate and prepare written data summaries and knowledge of chemicals and requirements for safe handling procedures.
• Skills to work in a laboratory and with concepts, principles, and conduct of research, which includes skills to follow specific protocols for data collection, and conduct analyses of lab results and follow GLP standards.

PREFERRED QUALIFICATIONS

Preferred Education/Experience:            

• Experience working in a laboratory and with concepts, principles, and conduct of research.
• Experience in the use and application of electron microscopes in conducting research analyses.
• Experience in laboratory safety and proper use, handling, monitoring, measurement and disposal of radioisotopes, carcinogens, and biohazardous materials/substances.
• Applied work experience to maintain lab notebooks and keep accurate and organized lab records.

Preferred Knowledge, Skills, and Abilities (KSA) :

• Analytical skills to troubleshoot problems and prepare medium and solutions including knowledge of chemistry to prepare solutions or reagents for lab experiments.
• Knowledge of safety regulations, reporting requirements, record keeping and disposal of chemicals and radioactive chemicals.
• Knowledge of standard laboratory equipment and supplies.
• Skills to work on several projects simultaneously and to switch focus as needed.
• Knowledge of purchasing procedures; skills to maintain purchasing records and chemical inventories; and to store and organize in appropriate locations.

SPECIAL REQUIREMENTS

Background Check

This position is a critical position and subject to a background check. Employment is contingent upon successful completion of background investigation including criminal history and identity checks.

The University of California has implemented a SARS-CoV-2 (COVID-19) Vaccination Program SARS-CoV-2 Vaccination Policy (ucop.edu) covering all employees.  To be compliant with the policy, employees must submit proof of vaccination or a University-approved exception or deferral.

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The University of California is an Equal Opportunity/Affirmative Action Employer advancing inclusive excellence.  All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, protected veteran status, or other protected categories covered by the UC nondiscrimination policy.