Junior Specialist - Urbano

University of California Davis, United States

Updated: 4 months ago
Location: Davis, CALIFORNIA

Details

Posted: 04-Jan-24

Location: Davis, California

Type: Full-time

Salary: Open

Categories:


Research - Laboratory/Non-Laboratory
Staff/Administrative

Internal Number: 4906627



Junior Specialist - Urbano
Position Overview:
A reasonable estimate for this position is $4,275 per month at Step 1 or $4,550 at Step 2
I. RESEARCH (80%)
This position will involve research in the area of microbe-host interactions investigating fundamental biological processes that influence the outcome of human and animal infections. Research will include the genetic manipulation of cell lines and microbial organisms to evaluate the contribution of candidate genes to disease. Methodologies may include CRISPR-Cas9 knockout methods, allelic exchange mutagenesis, recombineering, and genomic or sub-genomic genetic screens. Additional methodologies will involve molecular cloning methods to generate fluorescent fusion proteins that will aid in the characterization of genes of interest. Imaging assays will incorporate super-resolution, confocal, and/or epifluorescence microscopy on live and fixed samples. Quantitative approaches will be applied to evaluate gene transcript and protein expression (e.g., QPCR, RNA-seq, gel electrophoresis and Western Blots). Other methodologies will include immunostaining methods to determine protein sub-cellular localization, pathogen proliferation assays, intracellular motility and cell-to-cell dissemination assays. Ultimately, the successful candidate will work to characterize immunity proteins with previously unknown roles in microbial pathogenesis and host defense. The successful candidate will summarize research findings in progress reports, manuscripts, and grants. Participating in writing and publication of manuscripts in collaboration with the PI and other lab members is also expected
II. PROFESSIONAL COMPETENCE AND ACTIVITY (10%)
The candidate will participate in lab meetings, joint lab meetings, and journal clubs. Additional activities will include laboratory maintenance, assisting the PI with activities related to regulatory compliance (e.g., BUA), chemical inventory, maintaining laboratory protocols and training records, ordering supplies and interacting with vendors. When appropriate, the candidate will present data and participate in grant and publication writing.
III. UNIVERSITY AND PUBLIC SERVICE (10%)
The candidate will assist in the recruitment, laboratory training, and research of undergraduate students. Training will include basic laboratory technique and laboratory safety. Subject to funding availability, the candidate will present at regional meetings and/or national conferences.
QUALIFICATIONS
Basic qualifications (required at time of application)

  • Bachelor's degree in Biological Sciences, Biomedical Engineering, Immunology, Microbiology, Molecular and Cellular Biology, Genetics/Genomics, or related field
  • Previous laboratory experience
    Preferred qualifications (other preferred, but not required, qualifications for the position)
  • Demonstrated knowledge of concepts related to microbe-host interactions, biomechanics, the cytoskeleton, and/or actin dynamics
  • Laboratory experience working with bacterial pathogens and/or immune cells
  • Experience with genetic manipulation of bacteria and/or cell lines
  • Experience in molecular biology, cloning, and biochemical methods
  • Experience with microscopy and image analysis
  • Experience quantifying biomechanical parameters
    (e.g., force, tension, velocity)
  • Data science, or biostatistics skills
    UC Davis is a vibrant academic environment that offers multiple opportunities for attending seminars and interacting with other groups that are interested in Microbiology and Immunology within the Schools of Medicine, Veterinary Medicine, and the College of Biological Sciences.
    Applications from individuals with background in microbiology, immunology, bioengineering, cellular or actin biology are equally encouraged
    To apply, visit https://recruit.ucdavis.edu/JPF06236
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    About University of California Davis
    UC Davis is the home of the Aggies — go-getters, change makers and problem solvers who make their mark at one of the top public universities in the United States. Since we first opened in 1908, we’ve been known for standout academics, sustainability and Aggie Pride as well as valuing the Northern California lifestyle. These themes are woven into our 100-plus-year history and our reputation for solving problems related to food, health, the environment and society.Our 5,300-acre campus is in the city of Davis, a vibrant college town of about 68,000 located in Yolo County. The state capital is 20 minutes away, and world-class destinations such as the San Francisco Bay Area, Lake Tahoe and the Napa Valley are within a two-hour drive.
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