Improving Peptide Identification By Making Use of All Levels of Liquid Chromatography-Tandem Mass Spectrometry Analysis
RAP opportunity at National Institute of Standards and Technology NIST
Improving Peptide Identification By Making Use of All Levels of Liquid Chromatography-Tandem Mass Spectrometry Analysis
Location
Material Measurement Laboratory, Biomolecular Measurement Division
opportunity location
50.64.51.C0818 Gaithersburg, MD
NIST only participates in the February and August reviews.
Advisers
name email phone
Meghan Catherine Burke Harris [email protected] 301-975-5631
Description
This project aims to leverage sample preparation methods, state-of-the-art instrumentation, and custom software algorithms to improve methods for peptide identification from raw mass spectral data. The use of orthogonal information such as multi-enzyme digestions, to verify the presence of a peptide using different proteases, and ion mobility adds layers of confidence to a given identification. Individuals with a background in mass spectrometry or software development are encouraged to apply.
key words
mass spectrometry; liquid chromatography; mass spectral library; proteomics; peptide identification
Eligibility
Citizenship: Open to U.S. citizens
Level: Open to Postdoctoral applicants
Stipend
Base Stipend Travel Allotment Supplementation
$82,764.00 $3,000.00
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