Head of Mass Spectrometry Core Facility

Updated: about 2 years ago
Location: San Diego, CALIFORNIA
Deadline: The position may have been removed or expired!

Position Description:

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Encodia is a rapidly growing platform company that is developing a new generation of protein analysis tools based on single-molecule protein sequencing. Our goal is to make protein sequencing easy and ubiquitous by using a novel reverse-translation technology that turns peptide sequences into DNA. The DNA can be read by a DNA sequencer, providing a path to breakthrough proteomics research at a scale that is not practical or cost-effective using current technologies. For more information, please visit our website at 

https://www.encodia.com/

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HEAD OF MASS SPECTROMETRY CORE FACILITY

Encodia is seeking to recruit a passionate mass spectrometry scientist to helm our MS core facility and lead experimental design and data interpretation across a full complement of biomolecules including small molecules, peptides, proteins and oligonucleotides as we empower proteomics through the development of our ProteoCode platform.


Qualifications:
  • PhD in Chemistry, Biochemistry, or related field with 5+ years of experience in a biotechnology or (bio)pharmaceutical setting (title commensurate to experience level)
  • Proficiency in quantitative proteomics techniques; highlights could include analysis of post-translational modifications, labeled and label-free quantification methods 
  • Expertise with operation and method development on nanoflow liquid chromatography systems and hybrid mass spectrometers along with their data analysis tools (eg. MaxQuant, Skyline, etc.)
  • Experience in H/UPLC testing and method development
  • Expertise in impurity and unknown compound ID using mass spectrometry
  • Understanding of organic chemistry and reaction mechanism
  • Team oriented, collaborative, excellent verbal and written communication skill 

HIGHLY DESIRABLE


  • Experience using MS to analyze a range of biomolecules: proteins, peptides, small molecules, oligonucleotides, antibodies 
  • Experience conducting MS acquisitions in a variety of environments: SQ, Q-TOF, ion trap
  • Experience in organic chemistry synthesis and/or bioconjugation
  • Working knowledge in assay development to characterize the in vitro interactions of biological macromolecules
  • Technical team and/or project leadership experience

Encodia requires all on-site employees to be fully vaccinated for COVID-19 and to provide proof of vaccination at time of hire. This requirement extends to candidates for employment in order to participate in on-site interviews. Any candidate who is unable to meet the requirement may participate virtually in the interview process. As required by applicable law, the Company will consider requests for reasonable accommodations from this vaccine requirement where they do not cause Encodia undue hardship or pose a direct threat to the health and safety of others. Please let us know if you require a vaccination accommodation and a member of our Human Resources team will contact you.

RESPONSIBILITIES:


  • Creating and managing a best-in-class mass spectrometry ecosystem to make MS a lynchpin analytical readout across Encodia: proteomics, synthesis, QC, trace analysis
  • Innovating and directing fit-for-purpose MS workflows: Sample preparation, MS acquisition, data processing, data analysis, report production, presentation
  • Directing the consolidation and automation of heavy use workflows in collaboration with Encodia’s bioinformatics team
  • Empowering Encodia scientists with leadership around MS data interpretation and data QC
  • Managing a technical core facility team
  • Distilling, organizing and synthesizing results into cogent and transparent visual aids and presentations to a wide range of both scientific and business audiences
  • Contributing to the Encodia’s strategic direction and IP portfolio

BENEFITS:

Encodia is an Equal Opportunity Employer. We offer a competitive and comprehensive employee benefits package including medical, dental, and vision, LTD, paid vacation, and a stock plan.

We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, gender, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status. We are committed to building diverse teams, and we strive to create an inclusive workplace that cultivates bold innovation through collaboration and empowers our people to unleash their full potential.

Encodia requires all employees to be fully vaccinated against COVID-19 by their start date. We will reasonably accommodate employees who cannot get vaccinated because of medical reasons or sincerely-held religious beliefs to the extent that any such accommodation does not pose an undue hardship for the company.


To Apply:

For more information and to apply to the available position, please visit this website: 

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