Cell Biology of Neurodegeneration

National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD and surrounding area

A postdoctoral position is available in the laboratory of Dr. Priyanka Narayan in the Genetics and Biochemistry Branch, NIDDK (joint appointment with NINDS) to investigate and modulate the cellular pathways perturbed by neurodegenerative disease risk factors using human induced pluripotent stem cell (iPSC)-derived neural cell types. Our lab is located in Building 10 on the main NIH Campus in Bethesda, MD.

Genome wide association studies have identified genetic factors that increase risk for neurodegenerative diseases like Alzheimer’s disease. A number of these risk factors are shared between multiple neurodegenerative diseases with diverse pathologies and clinical presentations. Our lab works on multiple questions including: (1) How do disease risk factors alter the cellular pathways to increase susceptibility to disease processes? (2) Can we identify genetic and chemical modulators of these cellular perturbations to prevent or reverse the detrimental effects of risk factors? We use a combination of genetics, biochemistry, molecular biology, and human iPSC-derived neuronal and glial cell types to answer these questions. We envision that our findings can accelerate the development of novel therapeutic or preventative strategies for neurodegenerative diseases. Additional information be found at:

Candidates must hold a doctoral degree (PhD or the equivalent) by the start date of the fellowship in molecular biology, genetics, biochemistry, cell biology, neuroscience, or a related field and should have less than 5 years of post-doctoral experience. Those with experience in iPSC work are highly encouraged to apply. Positions at the NIH are subject to a background investigation.

To apply, interested individuals should email their CV, a cover letter summarizing current and future research interests, and contact information for three references to:

Application Deadline: October 31, 2022

Individuals from underrepresented groups are encouraged to apply! The NIH is dedicated to building a diverse community in its training and employment programs.