A postdoctoral position is available at the DNA Replication Group (PI: Mirit I. Aladjem, Ph.D.), in collaboration with the Molecular Pharmacology Group (PI: Dr. Yves Pommier, M.D., Ph.D.) of the Developmental Therapeutics Branch, CCR, NCI in Bethesda, Maryland. Our groups aim to understand mechanistic insights into cellular networks that modulate cancer cell proliferation and identify targets for intervention in cancer. Since many regulatory feedback pathways are deregulated in cancer cells, the results of our studies will help our understanding of cancer biology and the mechanisms underlying therapeutic strategies.
The research projects are built on our recent comprehensive analyses of distinct protein-DNA interactions and chromatin transactions that modulate cancer cell proliferation and on novel associations between the sensitivity of malignant cells to anti-cancer therapy and gene expression and epigenetics features of cancer cells. The successful applicant will spearhead investigations of chromatin modifications that affect DNA synthesis and mine a unique dataset associating the genetic and epigenetic properties of cancer cells and patient samples with the sensitivity to anti-cancer therapy. There will also be an opportunity to develop and implement novel methods for data mining and analysis.
Training opportunities are augmented by collaborations with colleagues, physicians and pharmacologists from the intramural and extramural communities. Fellows are encouraged to take advantage of formal, focused courses (e.g., training in bioinformatics and translational research), actively engage in mentoring and participate in a variety of community activities including the NIH’s Cell Cycle Interest Group, DNA Repair Interest Group and the NCI's Center of Excellence in Chromosome Biology.
Qualifications:
PhD or equivalent in bioinformatics or computational biology
To Apply:
Please contact Dr. Aladjem [email protected] , submit a CV/resume, bibliography and a statement of interest.
The NIH is dedicated to building community in its training and employment programs and encourage the application and nominations of qualified women, minorities, and individuals with disabilities. DHHS and NIH are Equal Opportunity Employers.
Similar Positions
-
Metrology For Epigenetics, NIST, United States, 5 days ago
RAP opportunity at National Institute of Standards and Technology NIST Metrology for Epigenetics Location Material Measurement Laboratory, Biosystems and Biomaterials Division opportunity loca...
-
Microfluidics And Lab On A Chip Technologies For Controlled Molecular Self Assembly, Analytical Biochemistry, And Multiplexed Measurements, NIST, United States, 5 days ago
RAP opportunity at National Institute of Standards and Technology NIST Microfluidics and Lab-on-a-Chip Technologies for Controlled Molecular Self-Assembly, Analytical Biochemistry, and Multipl...
-
Postdoc Research Associate , Washington University in St. Louis, United States, 21 days ago
Postdoctoral Research Associate- Pulmonary & Critical Care Medicine Scheduled Hours Full Time Position Summary A postdoctoral position is available immediately at the laboratory of Dr. Choudhury i...
-
Postdoc Research Associate , Washington University in St. Louis, United States, 20 days ago
Postdoctoral Research Associate- Pulmonary & Critical Care Medicine Scheduled Hours Full Time Position Summary A postdoctoral position is available immediately at the laboratory of Dr. Choudhury i...
-
Microfluidics For Biotherapeutics Measurements, NIST, United States, 5 days ago
RAP opportunity at National Institute of Standards and Technology NIST Microfluidics for Biotherapeutics Measurements Location Material Measurement Laboratory, Biomolecular Measurement Divisio...
-
Microsystems For Massively Multiplexed Molecular Biology, NIST, United States, 5 days ago
RAP opportunity at National Institute of Standards and Technology NIST Microsystems for Massively Multiplexed Molecular Biology Location Material Measurement Laboratory, Biosystems and Biomate...