Updated: about 1 month ago
Location: Durham, NORTH CAROLINA

This Position is Grant Funded

School of Medicine Established in 1930, Duke University School of Medicine is the youngest of the nation's top medical schools. Ranked sixth among medical schools in the nation, the School takes pride in being an inclusive community of outstanding learners, investigators, clinicians, and staff where interdisciplinary collaboration is embraced and great ideas accelerate translation of fundamental scientific discoveries to improve human health locally and around the globe. Composed of more than 2,500 faculty physicians and researchers, more than 1,300 students, and more than 6,000 staff, the Duke University School of Medicine along with the Duke University School of Nursing, Duke University Health System and the Private Diagnostic Clinic (PDC) comprise Duke Health. a world-class academic medical center. The Health System encompasses Duke University Hospital, Duke Regional Hospital, Duke Raleigh Hospital, Duke Primary Care, Duke Home and Hospice, Duke Health and Wellness, and multiple affiliations.


Duke Human Vaccine Institute


The Duke Human Vaccine Institute (DHVI) is seeking a highly motivated bioinformatician to join our dynamic team of scientists and computational biologists. As an integral team member, you will contribute to our mission of vaccine design by leveraging bioinformatics tools to analyze immune responses to infections and vaccinations, focusing primarily on lymphocyte B cells, antibodies, and how they interact with antigens. This role offers an exciting opportunity to analyze complex, high-throughput omics data sets and assist in developing innovative computational methodologies. We advocate a collaborative work culture, offering opportunities for skill enhancement and career growth. Join our institute-wide initiative to have a chance to improve human health and make a substantial impact on the field of vaccine development.


  • Design and develop cutting-edge computational strategies to analyze large multi-omics data sets, in particular single-cell transcriptomics, and immune profiling data sets.
  • Collaborate with research teams across DHVI, providing bioinformatics training, consultation, application support, and development.
  • Create and manage software and web-based bioinformatics tools for B cell repertoire sequence data analysis.
  • Contribute to the drafting and publication of research findings.
  • Engage in group activities, sharing expertise and promoting best practices within our group.


  • Education/Training: Work requires a B.S. in Bioinformatics or the Biological Sciences with demonstrable computational skills; or a B.S. in Computer Science with a strong interest in Biology/Genomics. M.S. preferred.
  • Experience: Or an equivalent combination of relevant education and/or experience.


  • Proficiency in a programming language such as Python, R, and Perl.
  • Experience with statistical methods and statistical analysis.
  • Comfortable operating in a Linux-based environment.
  • Familiarity with Next-Generation Sequencing Data, especially single-cell technologies, would be highly advantageous.
  • Experience in a high-performance computing environment is a plus.


  • Experience with web design is a plus.
  • Strong analytical and problem-solving skills.
  • Excellent communication and interpersonal skills.
  • Capability to work independently and as part of a team.
  • Ability to adapt to changing requirements and learn new technologies.

If you are a highly motivated bioinformatician who is looking for a challenging and rewarding opportunity, we encourage you to apply!

Duke is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas—an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

Essential Physical Job Functions: Certain jobs at Duke University and Duke University Health System may include essentialjob functions that require specific physical and/or mental abilities. Additional information and provision for requests for reasonable accommodation will be provided by each hiring department.

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