Associate in Research

Biomedical Engineering, United States

Updated: 2 days ago
Location: Durham, NORTH CAROLINA
Position ID:Duke -BME -DUKECHATTERJEE [#24548, 1420]
Position Title: 
Position Type:Other
Position Location:Durham, North Carolina 27708, United States [map ]
Subject Area: Biomedical Engineering / Biomedical Engineering
Appl Deadline: (posted 2023/03/16, listed until 2023/09/16)
Position Description:  Apply    
Associate in Research in Deep Learning-Based Protein Design at Duke University 
The Programmable Biology Group (https://www.chatterjeelab.com/ ) at Duke University, led by incoming Professor Pranam Chatterjee, leverages deep learning-based protein design to develop the next generation of programmable tools for: 
Genome Editing: https://news.mit.edu/2020/nature-inspired-crispr-enzymes-expansive-genome-editing-0519 Targeted Protein Editing: https://news.mit.edu/2020/peptide-binds-covid-19-proteins-0622 
Cell Engineering: https://wyss.harvard.edu/news/taking-the-guesswork-out-of-genetic-engineering/  
In the immediate future, we seek to apply our deep learning-designed editors to correct disease-related mutations and to degrade pathogenic proteins for therapeutic purposes. Our long-term goals are to employ our novel cell engineering methods to generate functional gametes, as well as other ovarian cell types, from stem cells. 
To develop the next generation of biotechnology solutions, we seek motivated computer scientists with experience in the following areas: 
● Natural language processing (Transformers, seq2seq models) 
● Physics-based protein modeling (Rosetta, AMBER, etc.) 
● Generative algorithms (Diffusion, GPT algorithms) 
Overall, the ideal candidate will be excited to apply their computational expertise in new, innovative directions, and work with a dynamic team made up of both experimentalists and computer scientists! 
Expected Start Date: July 1, 2023 
Application Materials Required: 
● Cover letter 
● Curriculum Vitae 
● Names and contact information of three references
Duke University is an Affirmative Action/Equal Opportunity Employer committed to providing employment opportunity without regard to an individual's age, color, disability, gender, gender expression, gender identity, genetic information, national origin, race, religion, sex, sexual orientation, or veteran status.

Duke aspires to create a community built on collaboration, innovation, creativity, and belonging. Our collective success depends on the robust exchange of ideas-an exchange that is best when the rich diversity of our perspectives, backgrounds, and experiences flourishes. To achieve this exchange, it is essential that all members of the community feel secure and welcome, that the contributions of all individuals are respected, and that all voices are heard. All members of our community have a responsibility to uphold these values.

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