Assistant Research Professor of Pathology & Laboratory Medicine

Indiana University, United States

Updated: 13 days ago
Location: Indiana, PENNSYLVANIA
Deadline: ;

Posting Details
Position Details


Title Assistant Research Professor of Pathology & Laboratory Medicine
Specific Title
Appointment Type Scientist Track Faculty
Department IUSM - Pathology & Laboratory Medicine
Campus IU School of Medicine Indianapolis
Position Summary
The Indiana University School of Medicine has an exciting opportunity of an assistant research professor within the team led by Drs. Anita Bellail, and Chunhai “Charlie” Hao, in Department of Pathology & Laboratory Medicine for protein structure-guided drug discovery, which focuses now on anticancer and antiaging drugs.
Our team investigates targeted protein degradation for the discovery of small molecule degraders. The team has recently reported the first small molecule degraders of SUMO1 protein as novel anticancer drugs (Bellail et al. Science Translational Medicine 2021, 13:e12947). The team has submitted a manuscript on the discovery of small-molecule degraders of amyloid procurer protein (APP) for treatment of Alzheimer’s disease. The team is currently working on Cryo-EM and NMR structures of molecule degrader-induced protein complex and thus developing the structure-guided and AI-powered drug design.
Primary Job Duties and Responsibilities:
- Experimental design, execution, interpretation, and publication
- Development of molecular and biochemical methodologies
- Collaboration with team members
The position is funded by NIH and other foundation grants and salary is based on the IUSM standards on the experience of the applicants. The position is available for an initial appointment of one year, renewable for subsequent years.
­­
As the nation’s largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and wellbeing for all throughout the state of Indiana.
Indianapolis is the capital and most populous city in the State of Indiana. It is growing economically thanks to a strong corporate base anchored by the life sciences. Indiana is home to one of the largest concentrations of health sciences companies in the nation. Indianapolis has a sophisticated blend of charm and culture with a wonderful balance of business and leisure. The growing residential base is supported by rich amenities and quality of life – the city possesses a variety of professional sports, arts venues and outdoor recreation areas. Residents of this dynamic city, and surrounding suburbs, enjoy leading educational systems and top-ranked universities, paired with a diverse population. Indianapolis International Airport is a top-ranked international airport, being named “Best Airport in North America” by Airports Council International for many years. For additional information on life in Indy: https://faculty.medicine.iu.edu/relocation
Basic Qualifications
Ph.D. degree in the field of structural biology is required.
Minimum Qualifications:
  • Research experience in Cryo-EM, X-ray crystallography and NMR structural biology as evidenced by publications.
  • Strong biochemistry and molecular biology background to generate and characterize the recombinant proteins for structural studies.
  • A strong commitment to experimental work is expected.
  • Computer skills and experience on Linux and Linux workstation.
  • A naturally collaborative and self-motivated style is necessary to work effectively in a fast-paced, highly integrated team environment.
  • Excellent written and oral communication skills.
  • Demonstrated ability to write peer reviewed quality work, and able to present at a local, domestic and international conferences.
Department Contact for Questions
Charlie Hao, MD, PhD.
Bicentennial Professor
Department of Pathology and Laboratory Medicine
Additional Qualifications
Special Instructions
Priority Application Review Deadline
Expected Start Date
OAA # IUSM-01920-2024

Similar Positions