Advanced Regulatory Science for Nanotechnology

RAP opportunity at National Institute of Standards and Technology     NIST

Advanced Regulatory Science for Nanotechnology

Location

Material Measurement Laboratory, Materials Measurement Science Division

opportunity location
50.64.31.C0043 Gaithersburg, MD

NIST only participates in the February and August reviews.

Advisers
name email phone
Justin M. Gorham [email protected] 301.975.5944
Vincent A. Hackley [email protected] 301.975.5790
John Michael Pettibone [email protected] 301.975.5656
Description

This Research Opportunity addresses the needs of regulatory science for nanotechnology based products, including therapeutics, biomedical devices, coatings, food-related materials, and personal care. Work emphasizes the development of analytical methods for quantitative measurement of engineered nanoparticle properties, including bulk and surface composition, surface reactivity, stability, physical state and functional performance (nano-analytics). Research focuses on (1) the development of measurement methods and instrumentation to determine molecular adsorption onto nanoparticles, nanoparticle corona composition, surface density, and conformation of ligands; (2) the differentiation between multiple functional ligands co-conjugated to the nanoparticle surface and to assess the effect of surface coatings on nanoparticle stability and functionality; (3) the development of hyphenated techniques that combine separation with multiple detection modes for size-resolved analysis of nanoparticle core and surface composition; (4) the development of analytical methods for detection and monitoring of engineered nanoparticles and their transformational products in biological systems, including use of stable isotopes combined with mass spectrometry; (5) the development of methods for separation by size/shape/aspect ratio/chemistry; and (6) the development of surface probe techniques to measure properties of nanoparticle coatings.

key words

Nanolytics; Metrology; Nanotube; Nanorod; Nanomaterial; Nanoparticle; Nanotechnology; Surface chemistry; Physicochemical properties; Surface functionalization; Measurement; Adsorption; Ligand; Corona; Environment; Hyphenated; Mass spectrometry; Field flow fractionation; Surface probe;

Eligibility

Citizenship:  Open to U.S. citizens

Level:  Open to Postdoctoral applicants

Stipend
Base Stipend Travel Allotment Supplementation
$82,764.00 $3,000.00