Senior Postdoctoral Scientist
UNIVERSITY OF OXFORD - , Jenner Institute, Clinical Centre for Vaccinology and Translational Medicine (CCVTM), Old Road Campus, Headington, Oxford, OX3 7LE
Grade 8: £41,526 - £49,553 per annum with a discretionary range to £54,131 per annum
We are seeking to appoint a Senior Postdoctoral Scientist to join Professor Christine Rollier & Professor Cal MacLennan’s Gonococcal Vaccine Group. The programme focuses on development of a novel outer membrane vesicle (OMV)-based vaccine through to GMP production and Phase 1 trial. This is an opportunity to be a key part of the team and conduct preclinical and clinical development of our OMV vaccine.
As Senior Post Doctoral Scientist, you will develop processes, assays and methodologies to optimize the production of the gonococcal vaccine with a view to tech transfer to the Clinical BioManufacturing Facility. You will be responsible for establishing research cell banks of the vaccine production strain, vaccine CMC (Chemistry, Manufacturing and Controls) and scale up of production methods, developing a set of Standard Operating Procedures ready for tech transfer, developing the analytical assays ready for qualification, and overseeing immunogenicity and efficacy testing in mice. As part of this senior position, you will share responsibility for shaping the group’s research plans by leading scientifically and operationally on novel exploratory clinical immunology readouts, organising/ delegating tasks to other members of the team as appropriate; coach other members of the group on relevant specialist methodologies as required; contribute knowledge and expertise to other group research priorities; supervise students and one or more research assistants. In addition, you will manage collaborations with national and international partner institutions and research groups, regularly write research articles for peer-reviewed journals to describe findings, as well as present data at internal/external seminars and conferences, be involved in grant management.
You must have a doctoral degree (or equivalent) in a subject relevant to vaccine production and CMC, a strong publication record, experience of advanced development of methodologies in microbiology, immunology and analytical assays, the ability to research complex issues and interpret, analyse, and present scientific data and write factual reports. You will need well-developed organisation skills to be able to manage multiple projects with competing priorities effectively, the ability to independently plan and manage a research project, including a research budget, the ability to raise research funds through making grant applications, and have excellent communication, interpersonal skills, and ability to work effectively with others. Experience of working is industry is desirable.
Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.
Please note, the appointed applicant will require security screening.
This position is of fixed-term for 20 months in the first instance with good prospect of further extension and funded by US funding.
Only applications received before 12 midday, on 4 November 2020 will be considered. Please quote 147960 on all correspondence.
Closing Date: 04-NOV-2020 12:00
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