Senior Bioinformatician, Oxford-GSK Institute for Molecular and Computational Medicine

Are you looking for a new and exciting career opportunity? The Oxford-GSK IMCM are seeking a Senior Bioinformatician, to join the team! The initial focus of the IMCM is on neurodegeneration and the central nervous system, specifically Alzheimer’s disease, Parkinson’s disease and amyotrophic lateral sclerosis.

In this role, you will plan, lead and conduct processing and detailed analysis of a variety of ‘omics datasets, including bulk and single cell transcriptomic data, whole-genome and exome DNA sequencing data, proteomic data and metabolomic data across a range of parallel projects. You will provide expert bioinformatics advice to the IMCM research project teams and identify, define and plan new analyses that will progress the IMCM research projects. In addition, you will keep meticulous, detailed records of your work and commit to performing cloud-based analyses on the IMCM data platform. Working closely with the Technical Lead in Bioinformatics, you will ensure alignment of bioinformatics approaches and methods across Oxford-GSK IMCM projects, enabling cross-project analysis where appropriate. Exploring and implementing cutting-edge approaches to analysis of multimodal datasets to keep the Oxford-GSK IMCM at the forefront of the bioinformatics field will be an important part of this role.

As Senior Bioinformatician, you will bring a wealth of knowledge and experience handling and analysing various types of ‘omics data types, such as RNA-Seq, whole genome or exome sequencing data, single cell profiling, ChIP-Seq, proteomics, and metabolomics. It is essential that you hold a PhD/DPhil in bioinformatics, computational biology, biostatistics, applied mathematics, or related discipline. You will have demonstrable specialist bioinformatics knowledge, skill and experience to develop and oversee large programmes of technical work to a successful conclusion by agreed deadlines. Additionally, self-motivation and the ability to combine strategic thinking with hands-on bioinformatics skills, with a drive for performance and quality improvement are essential qualities for this role. Previous experience of working on neuroscience projects, such as on Parkinson’s disease, Alzheimer’s disease, ALS or another neurodegenerative disease would be highly desirable.

Applications for this vacancy are to be made online and you will be required to upload a supporting statement and CV as part of your online application. Your supporting statement must explain how you meet each of the selection criteria for the post using examples of your skills and experience.

This position is offered full time on a fixed term contract until 30 September 2027 and is funded by GSK.

Only applications received before 12 midday on 12 March 2024 will be considered. Please quote 171148 on all correspondence.