The Merkle laboratory are seeking a Research Laboratory Coordinator to provide technical and organisational support essential to the smooth operation of the Merkle laboratory, by coordinating these activities with the PI (Florian Merkle,www.merklelab.org
) to help ensure that research aims are met on budget and in a timely manner.
The Merkle laboratory uses emerging technologies to harness the complementary strengths of animal models and human pluripotent stem cell-based models in order to understand the mechanistic basis of common human neurological diseases. We focus on obesity and neurodegenerative disease, both of which are diseases of the brain that have a strong genetic basis, and for which there is a large, unmet need for new treatments. Identifying disease mechanisms and therapeutic targets are of central importance to our Department. To study these diseases, we use a combination of CRISPR gene editing, single-cell RNA sequencing, high content live and fixed cell imaging, and more standard molecular and cellular techniques. We also have a research programme that focuses on basic stem cell biology, specifically the selective pressures that exist in vitro and how these lead to the emergence of recurrent culture-acquired mutations. These efforts are funded by the MRC, Wellcome Trust, New York Stem Cell Foundation, and the Chan Zuckerberg Initiative, some of which provide training opportunities (e.g. open science and computational biology) for career development and an opportunity to interact with other world-class laboratories.
Fixed-term: The funds for this post are available for 2 years in the first instance.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment and a security check.
To apply online for this vacancy and to view further information about the role, please visit :
Closing Date: 29 April 2021
Please ensure that you outline how you match the criteria for the post and why you are applying for this role on the online application form.
Please include details of your referees, including e-mail address and phone number, one of which must be your most recent line manager.
Please quote reference RG24416 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
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