We have a postdoctoral position available to study host-virus interactions and coevolution in the group of Prof. Yorgo Modis in the University of Cambridge Department of Medicine. The Modis group is part of the Molecular Immunity Unit within the MRC Laboratory of Molecular Biology (MRC-LMB). We benefit from the outstanding scientific environment and infrastructure of the MRC-LMB, and from being part of the virology and immunology community as members of the Cambridge Institute of Therapeutic Immunology & Infectious Disease (CITIID).
The group's key research questions are: How do cells recognize viral RNA with the necessary sensitivity and specificity? How do cells repress expression of integrated viral genes? And what are the functions of endogenous viral genes that escape repression? We aim to understand these processes at the molecular level by integrating mechanistic insights from structural studies with functional validation in the cellular context. Our projects have important potential applications in global health.
We seek a highly motivated research scientist with a PhD in the biological, biochemical or biomedical sciences, and relevant research experience in protein biochemistry and macromolecular structure determination or protein bioinformatics. Candidates must have one or more first-author research article(s) published in a peer-reviewed journal or under review with a preprint available. Experience in eukaryotic expression systems, cell-based assays, immunofluorescence microscopy and bioinformatics is desirable.
Appointment at Research Associate is dependent on having a PhD, (or equivalent experience is recognised), including those who have submitted but not yet received their PhD. Where a PhD has yet to be awarded or submitted appointment will initially be made at Research Assistant and amended to Research Associate when the PhD is awarded.
The position is available for two years in the first instance and is funded by the Wellcome Trust.
Informal enquiries are welcomed and should be directed to Prof. Modis at [email protected]
Fixed-term: The funds for this post are available for 2 years in the first instance.
To apply online for this vacancy and to view further information about the role, please visit: http://www.jobs.cam.ac.uk/job/32423 .
Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.
Closing date: 26th June 2022
Interview date: to be confirmed
Please quote reference RC29055 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
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