Little is known about how eukaryotic pathogens move about in a vertebrate host. We have developed an experimental model based on trypanosome infection of transparent zebrafish larvae that enables the behaviour of trypanosomes and the response of the host to be investigated at single cell resolution in a live vertebrate host. A post-doctoral research assistant position is available to improve the experimental system by developing transgenic trypanosomes expressing sufficient fluorescent protein to allow time lapse imaging of trypanosome movement between tissues and identify any preferred locations for proliferation. Combining these trypanosomes with transgenic zebrafish lines with various immune cell lineages marked with a different fluorescent protein will enable us to characterise the cellular immune response to infection.
The position is funded for three years by an award from the Leverhulme Trust to Mark Carrington in Cambridge and Maria Forlenza in Wageningen. The successful applicant will be expected to work both in Cambridge (UK) and in Wageningen (The Netherlands), probably spending at least 12 months in each location. Applicants should have experience in one or both of the following: 1. Cell biology, preferably with protozoa. 2. Microscopy, preferably live cell imaging. A good background in basic Molecular Biology and/or zebrafish handling is desirable but not required.
Informal enquiries can be sent to Mark Carrington email@example.com and Maria Forlenza firstname.lastname@example.org
Fixed-term: The funds for this post are available for 3 years.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
If you have questions about the application process please email email@example.com
Please quote reference PH26088 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Research Associate (Storer Lab) (Fixed Term) , University of Cambridge ;, United Kingdom, 18 days ago
The Wellcome - Medical Research Council Cambridge Stem Cell Institute is an international centre of excellence for stem cell research and regenerative medicine. Scientists in the Institute collabo...
Advanced Research Assistant Genome Editing And Cellular R&D, Wellcome Trust Sanger Institute, United Kingdom, about 14 hours ago
We are seeking an enthusiastic Advanced Research Assistant to perform high throughput, transcription factor driven differentiation screens in human pluripotent stem cells to generate novel cell ty...
Bioinformatics Research Associate Cellular States And Genome Architecture (Fixed Term) , University of Cambridge ;, United Kingdom, 15 days ago
The Ahringer laboratory at the Wellcome/CRUK Gurdon Institute is seeking a talented and motivated Bioinformatics Research Associate to join their research laboratory. We study how control of regul...
Advanced Research Assistant, Wellcome Trust Sanger Institute, United Kingdom, about 14 hours ago
The Translational Cancer Genomics Team focuses on understanding the consequences of alterations in the DNA of cancer cells. We do this at scale using multiple approaches including drug sensitivit...
Senior Research Assistant, Wellcome Trust Sanger Institute, United Kingdom, about 14 hours ago
We are seeking a Senior Research Assistant to join the Cellular Operations (CellOps) division as part of the Gene Editing team. About the role: You will play a fundamental role in the generation o...
Research Assistant Neuroscience (Full Time/Part Time) , University of Cambridge ;, United Kingdom, 18 days ago
Applications are invited for a research assistant position in the group of Peter St George-Hyslop at the Cambridge Institute for Medical Research (CIMR) at the Biomedical Campus/University of Camb...