Research Associate (Lab Manager) (Fixed Term)

The Wellcome Trust - Medical Research Council Cambridge Stem Cell Institute is an international centre of excellence for stem cell research and regenerative medicine. Scientists in the Institute collaborate to advance our knowledge of various stem cell types and to perform pioneering work in translational research areas, providing the foundation for new medical treatments (https://www.stemcells.cam.ac.uk/ ).

The Vallier lab based at the Jeffrey Cheah Biomedical Centre takes advantage of human pluripotent stem cells and primary organoids to understand early human development and to generate cells with a clinical interest for modelling liver diseases and cell-based therapy. More precisely, they investigate the molecular mechanisms controlling cell fate decisions during human development and exploit the resulting knowledge to produce liver cells including hepatocytes and cholangiocytes. The resulting cells are currently used to study liver diseases and to develop regenerative medicine applications. Related research in the Vallier Lab includes genetic screen to identify new factors controlling liver diseases, identification of new targets for drug development against NAFLD/NASH, investigation of molecular mechanisms controlling liver organogenesis and regenerative processes in chronic liver diseases.

We are currently looking for a highly motivated individual to become the Research Associate (Lab Manager) of our research team devoted to understanding liver development and liver diseases. More precisely, we are looking for a dedicated Research Associate (Lab Manager) to support our ambitious and exciting projects aiming to develop new therapies against liver disease. The post holder will be in charge of procurement for our research team and to order consumables, to manage health and safety aspects, to monitor budget, to archive sample/cells and to write lab SOPs/protocols, to organise lab space and equipment maintenance. Importantly, the post holder will be offered multiple opportunities to participate in research projects. We are particularly interested in individual with a strong interest in developing protocols for molecular biology and genome wide analyses.

Homepage: https://www.stemcells.cam.ac.uk/research/pis/vallier

Requirements:

We are looking for candidates who hold a *PhD, or an equivalent research doctorate.

Skills and experience we are looking for include:

1) Research experience especially around lab management. 2) Strong experience in molecular biology. 3) Solid background in cell biology. 4) Experience with health and safety. 5) Solid experience with flow cytometry, QPCR, confocal imaging. 6) Experience with CHIP-Seq and RNA-Seq sample/library preparation would be highly advantageous.

We are specifically looking for candidates that have effective communication skills and the ability to work in a team. The successful candidate is expected to take a lead role in the laboratory. Proven capacity to organise lab activities and execute complex plan is essential while capacity to design, execute, and interpret own experiments would be useful.

*Appointment at Research Associate level is dependent on having a PhD or an equivalent research doctorate. Those who have submitted but not yet received their PhD will be appointed at Research Assistant level, which will be amended to Research Associate once PhD has been awarded. Salary Ranges: Research Assistant: £27,116 - £31,406 Research Associate: £33,309 - £40,927.

The closing date is Tuesday 5th October 2021, with interviews scheduled for Tuesday 12th October 2021.

Fixed-term: The funds for this post are available for 12 months in the first instance.

Once an offer of employment has been accepted, the successful candidate will be required to undergo a health assessment.

To apply online for this vacancy, please click on the 'Apply' button below. This will route you to the University's Web Recruitment System, where you will need to register an account (if you have not already) and log in before completing the online application form.

Please ensure that you upload a covering letter and CV in the Upload section of the online application. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.

Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.

Please quote reference PS28138 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Further information
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