A Postdoctoral Research Associate position is available within the MRC Metabolic Diseases Unit group co-led by Stephen O'Rahilly, Giles Yeo and Tony Coll at the Institute of Metabolic Science (IMS). This post will involve the study of molecular mechanisms underpinning the control of human metabolic pathways and their disruption in diseases such as obesity and will involve close collaboration with the group within the Institute that is led by Professor David Savage.
Scientists with a strong background in molecular and cell biology are encouraged to apply. An aptitude for and interest in developing more bioinformatic expertise would be advantageous. Some understanding of mammalian physiology and pathophysiology would be helpful as there will also be opportunities to model human diseases in lower organisms. The role holder will work closely with other members of the group on this research programme, in addition to developing their own independent research ideas and questions.
You will be expected to:
- Run a program of research investigating the molecular, cellular and organismal impact of mutations in human genes critical for metabolic health and disease
- present research work and data within the Institute, nationally and internationally and to prepare and submit research for publication in peer-reviewed journals
- assist in providing instruction to graduate students and other members of the research group in the standard molecular biology/biochemistry techniques and cellular imaging techniques
- assist the Principal Investigator in preparation of manuscripts and proposals/applications to funding bodies
To be considered for this position, you must have:
- a Ph.D. in cell biology or biochemistry, or a related discipline
- extensive research experience in a broad range of molecular and cell biology techniques such as recombinant DNA techniques, Western blotting, immunostaining and microscopy
- extensive experience with maintaining cells in culture and techniques for genome editing and/or siRNA and plasmid DNA delivery
- a degree of understanding of mammalian whole organism physiology and its integrative biology
- presentation skills backed up by a record of national and/or international presentations
- excellent interpersonal skills including ability to work effectively within a team
- the ability to impart knowledge and skills to graduate students and other members of the research team including graduate students
- the ability to troubleshoot experiments and for the development of novel research tools and platforms
- the ability to manage own workload in an organised way
- excellent organisational skills including ability to organize and participate in collaborative research initiatives and projects
- the ability to prepare and analyse data for publication in scientific journals and to present scientific data to peers in seminars and at conferences
Informal enquiries can be made to Professor Stephen O'Rahilly, MRC Metabolic Diseases Unit, Level 4, Wellcome-MRC Institute of Metabolic Science, Box 289 Addenbrooke's Hospital, Cambridge CB2 0QQ. Email: email@example.com
Fixed-term: The funds for this post are available for 24 months in the first instance.
Once an offer of employment has been accepted, the successful candidate will be required to undergo a basic disclosure (criminal records check) check, a health assessment and a security check.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Closing Date: 4 May 2021
Please ensure that you upload a covering letter and CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.
Please quote reference RG26261 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
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