Research Associate (Fixed Term)

Updated: about 1 month ago
Location: Cambridge, ENGLAND
Job Type: Permanent
Deadline: 18 Aug 2021

The negative impact that the COVID-19 pandemic is having on life and economies worldwide has raised awareness, both in the scientific community and the public, that airways are essential to our health and wellbeing. The 'Molecular Mechanisms of Airway Protection' research group, led by Vito Mennella, is focused on investigating pathways that are regulated during airway cells differentiation and mucociliary clearance, a key process protecting lung epithelial surface, when exposed to inhaled toxicants such as particulate matter, microplastics and infectious agents in healthy and disease states.

We are looking for a highly independent Research Associate with strong experience in airway biology and primary airway cellular models to join our group. The ideal candidate will have extensive supervision experience of trainees and a good track record of timely project delivery. The post-holder will be expected to develop their own projects, in line with the strategic interests of the lab.

The project offers the exciting opportunity to integrate airway molecular and cell biology methods with high-throughput protein-protein interactions methods to enable characterisation/obtain novel insights on multiprotein signalling complexes that regulate airway defence during environmental exposure. Knowledge of CRISPR/Cas9 methods, cell isolation methods for scRNAseq and lentivirus based assays are particularly welcomed.

The MRC Toxicology Unit is an internationally renowned institution focused on the delivery of field-changing mechanistic insights into toxicology and disease. The Unit is equipped with state-of-the-art facilities including super resolution microscopy, mass spectrometry, Cryo-EM, advanced flow-cytometry and offers excellent opportunities for postdoctoral development.

Applicants must hold a PhD in a relevant discipline such as molecular biology, cell biology or virology. The ability to work both independently and as part of a team, together with excellent communication and critical thinking skills are also essential.

Fixed-term: The funds for this post are available for 3 years in the first instance.

Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.

Informal enquiries are invited and can be directed to Vito Mennella (vm430@cam.ac.uk ).

If you have any queries regarding the application process, please contact Bronwen Chamberlain at bc535@mrc-tox.cam.ac.uk

Please quote reference PU27556 on your application and in any correspondence about this vacancy.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.


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