Research Assistant/ Postdoctoral Research Assistant in Molecular Biology of Cell Cycle Progression

Updated: 25 days ago

Grade 7: Salary in the range £31,604 – £34,520 p.a.

We are seeking to appoint a (postdoctoral) research assistant to join the Mitotic Progression group headed by Dr Ulrike Gruneberg. The Gruneberg lab studies the regulation of cell cycle progression and chromosome segregation in mammalian cells. The position is part of an interdisciplinary, collaborative BBSRC-funded project - ‘Systems-level characterisation of mammalian cell cycle transitions’. The goal of this post is to understand the dynamic characteristics of the metaphase-to-anaphase transition in untransformed human cells by combining state-of-the-art live-cell imaging and biochemical analysis with mathematical modelling.

The successful candidate will analyse the biochemical mechanisms regulating spindle assembly checkpoint function in mammalian tissue culture cells. The work will involve a broad range of cell biological and biochemical methods with a focus on Western blotting and immunofluorescence analysis of synchronised cell populations. Applicants are expected to be highly motivated, organised and reliable and have an excellent background in molecular and cell biology.

Applicants should possess a first class or upper second class degree in biochemistry or biomedical sciences or a PhD in a relevant lab based biological discipline. Previous lab experience in protein biochemistry, molecular biology or mammalian tissue culture is a requirement; experience with immunofluorescence analysis and live cell imaging would be a bonus.

This full-time post is fixed-term for 12 months in the first instance. Research Assistant position at a lower grade (Grade 6: £28,098 - £33,518 p.a.) may be offered with reasonable adjustment in responsibilities if a suitable candidate cannot be found to fill the Grade 7 position.

You will be required to upload a supporting statement and CV as part of your online application.

Only applications received before 12.00 midday on Monday 20 August 2018 can be considered. Interviews will be held shortly thereafter.


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