Fixed Term until 31 March 2022
About the Role
We have an exciting opportunity to join The Mary Lyon Centre at the Medical Research Council Harwell where you will provide technical support to a busy Genome Engineering service team.
You will be based within established laboratories involved in the generation and quality control of mouse targeted alleles and genotyping. You will work as part of a team and be responsible for performing a range of Molecular Biology techniques (including generation of CRISPR reagents, PCR, Sanger and long-read sequencing analysis, digital droplet PCR, non-radioactive Southern blotting and qPCR-based genotyping) and embryonic stem (ES) cell culture. Emphasis on particular techniques will vary according to service demand.
Main duties / key responsibilities:
Characterisation and quality control of genetically modified materials employing high end PCR-based techniques and non-radioactive Southern blotting. Genotyping. Sample management and communication of results. Some ES cell culture.
As the successful candidate you will have a BSc in Biological Sciences or related including an understanding of genome engineering techniques in animal models (gene targeting, CRISPR-based tools). You will have proven experience of wworking in a molecular biology laboratory, using techniques such as PCR, qPCR and cloning.
Attention to detail is essential for this role as you will need to demonstrate extensive experience in handling and analysing complex sequencing datasets. You will have excellent communication skills, be customer focused and be able to produce work at a high standard.
The role requires you to be, computer literate for the recording and communication of results. Previous experience with DNA sequence analysis software is essential.
MRC Harwell Institute is an international biological research centre at the forefront of the use of mammalian models to study genetics and human diseases. Located on the Harwell Campus, just south of Oxford, it is nestled amongst a vibrant community of leading science organisations. We aim to advance medicine through cutting-edge research into the genetic basis of disease. Our research programmes span an entire lifetime, from embryonic development to diseases of ageing. There are over 300 staff at the Institute made up of research scientists, technicians, animal carers, and business support personnel.
Choosing to come and work at the MRC (part of UKRI) means that you will have access to a whole host of benefits including 30 days annual leave per year + 10.5 public and privilege days, a defined benefit pension scheme and access to employee shopping/travel discounts and salary sacrifice cycle to work scheme. You will also get the chance to put the MRC and UKRI on your CV in the future.
How to apply
For full details of this post view: https://mrc.tal.net/vx/appcentre-ext/brand-3/candidate/so/pm/4/pl/1/opp/1469-Research-Assistant-MLC-1469/en-GB to complete an online application. Please include a cover letter describing your motivation for applying. Please quote reference number MLC 1469
Closing Date: 9th March 2021
Research Assistant Mlc 1577 , Medical Research Council, United Kingdom, about 20 hours ago
View Vacancy -- Research Assistant - MLC 1577 Open Date 12/05/2021, 16:30 Close Date 02/06/2021, 23:55 Research Institute MRC Harwell Institute Research Institute / Unit Information MRC Harwell ...
Postdoctoral Researcher In Haematopoietic Stem Cell Biology, University of Oxford, United Kingdom, about 17 hours ago
This is a re-advertisement and previous applicants need not apply We are seeking a motivated and enthusiastic Postdoctoral Researcher to lead a project using state-of-the-art techniques to study h...
Research Assistant In Single Cell Genomics, University of Oxford, United Kingdom, about 18 hours ago
The Mead Laboratory has pioneered the development and application of single cell technologies for the study of leukemia. This is an exciting opportunity to work on an innovative project translatin...
Postdoctoral Researcher, With Bioinformatics And Immunology Interests, University of Oxford, United Kingdom, about 5 hours ago
We are looking for a Postdoctoral Researcher with bioinformatics and immunology interests to work on an exciting opportunity as part of the Oxford Autoimmune Neurology Group, within the Nuffield D...
Research Assistant, University of Oxford, United Kingdom, about 18 hours ago
Applications are invited for a highly motivated Research Assistant in Cell and Molecular Biology of Transcription Factors, with proven experience in modern cell-biology and molecular biology metho...
Research Assistant And Laboratory Manager, University of Oxford, United Kingdom, about 18 hours ago
The Chapman laboratory is looking to recruit a talented and highly-motivated research assistant. You will oversee the laboratory’s mouse colony and undertake research that involves assisting labor...