Job Description
The Tan lab is looking for a post-doctoral candidate who will work with Assistant Professor Tan Yong Zi on biochemistry and structural biology under a project entitled Understanding the Structure and Function of Mammalian Membrane Proteins Involved in Human Diseases.
While membrane proteins only make up around 20% of the proteome, they constitute around 60% of drug targets. However, high resolution structural information is severely lacking for them, with only about 2% of the structures deposited in the public protein database (PDB) being annotated as membrane proteins. The Tan lab (www.tyzlab.com) strives to fill in this gap by targeting membrane proteins involved in human diseases such as cancer and diabetes. Our forte is using state-of-the-art single-particle cryogenic electron microscopy (cryo-EM) to obtain high-resolution atomic structures of these membrane proteins. We also actively work on methods development in cryo-EM that will help us answer our biological questions.
The Tan lab is generously funded by NRF Fellowship, MOE and NUS Presidential Young Professorship under the Department of Biological Sciences, NUS. We are a core member of the Centre for BioImaging Sciences' (CBIS), and have access to high-end cryo-EM microscopes, including a Titan Krios with K3 direct detector and energy filter.
Main Responsibilities
- Anchor cell culture work – including HEK293F and Sf9 cell work, as well as adherent cancer cell lines
Qualifications
Requirements
- Bachelor Degree in Science
- Experience with cell culture work required
- No structural biology experience required
- Candidates must uphold values of scientific integrity, honesty, teamwork and pride in their work
More Information
Location: Kent Ridge Campus
Organization: Science
Department : Biological Sciences
Employee Referral Eligible: No
Job requisition ID : 21752
Similar Positions
-
Research Fellow (Pharmacy), NATIONAL UNIVERSITY OF SINGAPORE, Singapore, 4 days ago
5 Dec 2023 Job Information Organisation/Company NATIONAL UNIVERSITY OF SINGAPORE Research Field Biological sciences Chemistry Researcher Profile Recognised Researcher (R2) Established Researcher (...
-
Research Fellow (Pharmacy), NATIONAL UNIVERSITY OF SINGAPORE, Singapore, 1 day ago
8 Dec 2023 Job Information Organisation/Company NATIONAL UNIVERSITY OF SINGAPORE Research Field Biological sciences Chemistry Researcher Profile First Stage Researcher (R1) Country Singapore Appli...
-
Post Doctoral Position In Membrane Based Nano Mechanobiology, Institute of Photonic Sciences, Luxembourg, about 17 hours ago
ICFO is offering a postdoctoral position to a well-qualified, highly motivated and dynamic young scientist who wishes to enhance his/her scientific career in a friendly and stimulating environment...
-
Postdoctoral Research Fellow (M/F/D) | Cell Growth Control In Health And Age Related Disease, Max Planck Institute for Biology of Ageing, Cologne, Germany, 28 days ago
Job Code: 23-2023 Job Offer from November 07, 2023 The Max Planck Research Group “Cell Growth Control in Health and Age-related Disease” headed by Dr. Constantinos Demetriades is looking for a ful...
-
Postdoc Position – Method Development Of Cryogenic 4 D Stem Imaging, Helmholtz, Germany, about 9 hours ago
Your Job: At the ER-C-3, the Structural Biology department of the ER-C, we use a comprehensive electron microscopy approach to study the biological structures of membrane-associated protein comple...
-
Postdoctoral Researcher Or Doctoral Researcher In Cell Communication Group, University of Helsinki, Finland, about 18 hours ago
The Cell Communication group led by Dr. Kari Vaahtomeri at the Translational Cancer Medicine Research Program, Faculty of Medicine, University of Helsinki invites applications for a fixed-term pos...