Principal Bioinformatician

Wellcome Trust Sanger Institute, United Kingdom

Updated: over 2 years ago
Location: Cambridge, ENGLAND
Deadline: The position may have been removed or expired!

The Opportunity:

The Teichmann lab is seeking an enthusiastic and skilled Principal Bioinformatician to contribute to the group’s cell atlasing research.

This is a unique opportunity to join a world-leading research team on a permanent contract, allowing you to contribute to the Human Cell Atlas project via your technical expertise and team management skills.   

Key responsibilities of this role include;

  • Working closely with Sarah Teichmann on the dry lab scientific and organizational strategy, with a responsibility for line managing dry lab roles
  • Leading or contributing as appropriate to publications
  • Analyse large scale multi-modal single cell genomics and spatial genomics data to characterise the cell states present in the tissue and their communication
  • Support and participate in the development of new computational methods to study cell state, cellular communication and gene regulatory networks
  • Suggest validation strategies to confirm hypotheses and predictions from 3) and 4) above

    •  About you:

    You will have a strong background in the management and analysis of large data sets, and will be looking for an opportunity to apply your experience and knowledge in the single cell field. With a passion for developing and supporting people, you will have supervised junior members in your previous roles.

    You will have proven experience in delivering collaborative projects, and will have strong communication skills.

     About the team:

    The Teichmann lab uses single-cell approaches, so called “cell atlas” technologies to combined with human genetics at the cellular level. To perform this research, we make use of state-of-the-art technological advances, including multi-modal single cell genomics (e.g., transcriptomics, chromatin accessibility, and protein expression) and spatial genomics (e.g. 10x Genomics Visium, FISH, in situ sequencing) technologies.  The team are significant contributors to the Human Cell Atlas and the Human Developmental Cell Atlas; international projects to systematically map all cells in the body across the lifespan. For more information about the HCA project click here.


    Please apply with your CV and a Cover Letter outlining your suitability for the role addressing the criteria set out above and in the job description.


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