Postdoctoral Scientist - PNAC - Dr Leo James - LMB 1710

A postdoctoral position is available in the James lab at the MRC Laboratory of Molecular Biology (LMB). We use multi-disciplinary approaches to address fundamental questions in infection and immunity. You will join a highly integrated and motivated team with diverse skills and expertise across molecular biology. You will investigate the mechanism of action of TRIM21 and use this information to guide our ongoing development of ‘Trim-Away’ protein depletion technology. A particular focus of this project will be the engineering of antibodies, TRIM21 and other factors to increase protein depletion efficiency and allow therapeutic applications.

Applicants should have a Ph.D. in molecular or cellular biology or biochemistry. Experience in cell assays, construct design or protein expression/engineering would be highly beneficial. A background in ubiquitin biology and/or antibody therapeutics would also be an advantage. An ability to work independently on dedicated projects is important but also to provide support and become involved with other projects in the lab.

The successful applicant will be awarded a 3-year Career Development Fellowship/ Postdoctoral Training Scheme position.  This is a training and development position for a Postdoctoral Scientist who has recently completed their doctoral studies, is moving into a new research discipline or has limited experience of key transferable skills. The MRC LMB has excellent scientific core facilities and training opportunities.

The MRC Laboratory of Molecular Biology is a research institute within UK Research and Innovation (UKRI).  UKRI is an entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found atwww.ukri.org .

Working for UKRI MRC provides a whole host of benefits including a defined benefit pension scheme, excellent holiday entitlement (40 ½ days including bank holidays and privilege days) and Benenden Healthcare membership.  You will also have access to employee shopping/ travel discounts, on site sport and social facilities, as well as salary sacrifice cycle to work schemes and childcare vouchers.

This role qualifies for endorsement by UKRI for a UK Global Talent Visa, for which the successful applicant is likely to be eligible to apply. Immigration costs (visa and health surcharge) can be reclaimed from UKRI after taking up the post (terms and conditions apply).

To apply and access full details of the vacancy please visit our job board at https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/1755 .

If you are unable to apply online please contact us at [email protected] .

Closing date: 30/11/2021

Final appointments will be subject to a pre-employment screening.

The Medical Research Council is an Equal Opportunities Employer who participates in the Disability Confident scheme.