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investigated in collaboration with the Glasgow Polyomics Facility (Dr R Burchmore, P Herzyk). This work is very much interdisciplinary, and adventurous, and requires not only a good foundation in basic molecular
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poor 5-year survival of <20% in the UK. Oncogene driven genomic instability leads to accumulation of DNA damage; this is a key and common phenomenon in AML cells, that could be therapeutically targeted