Postdoctoral Research Fellow

Fixed-term for 12 months initially, with a possible extension until 2027 (milestone based).

Full time - 35 hours per week.

The opportunity:

We are looking for a highly motivated postdoctoral fellow to pursue goals on our CRUK funded Biology to Prevention Project award. The project and PI team will provide resource and support for you to develop a novel transgenic model system in zebrafish, aimed at inducing somatic mutations with precise temporal control to model the earliest events of tumour initiation. The bioinformatician on the team will facilitate you to perform single-cell-Omics analysis to capture cellular state changes triggered by the mutation as well as environmental factors, thus potentially addressing the key question in cancer biology: How cells carrying oncogenic mutation transition toward a tumour initiating state. This is an opportunity to contribute to the research community focused on tumour initiation for better cancer prevention and early detection. This is also an opportunity to launch your own career by pioneering a model system with a key aim in mind but also pertains to broader impact in the zebrafish disease modelling field.

Your skills and attributes for success:

• A PhD in a life sciences subject and significant proven laboratory experience and knowledge of the research field as expected (Desirable).
• Expertise and highly competent in molecular cloning & CRISPR technologies.
• Evidence of a strong track-record in some aspect of cell and/or developmental biology and/or cancer biology.
• Evidence of a strong work ethic, independent thinking and ability to work as part of a research team.
• Readiness and ability to: contribute novel ideas to the project, learn new techniques as the need arises and overcome experimental difficulties. Vigorously maintain quality of research data generated.

Closing date: 25 April 2024 at 11:59pm.