Postdoctoral Research Associate in Synthetic Biology Engineering of Bacterial Superglues for Tailoring Microbial Communities

Updated: 4 months ago
Location: Oxford, ENGLAND
Deadline: 06 Jul 2018

We are seeking to appoint a Postdoctoral Research Associate to create a new generation of polyprotein teams and microbe teams. Through engineering and selection of a range of adhesion proteins from Gram-positive bacteria, the project will create giant programmable protein architectures. These assemblies should be powerful tools for a range of applications, including immuno-oncology, mechanobiology, vaccine assembly, and multi-enzyme organisation. In this project the controlled adhesion will be used to programme cell-cell interaction and thus direct the assembly of tailored microbial teams. We will provide training in unfamiliar methods.

Applicants should possess a PhD/DPhil, or be near completion of a PhD/DPhil, in biochemistry, cell biology, microbiology or a related area. You should be familiar with standard molecular biology approaches, recombinant protein expression, and protein chromatography and you should have applied these in your research. Excellent communication skills, including the ability to write for high impact publication and to present research outcomes at meetings are also essential as is the ability to keep detailed laboratory records. Skills and experience in fluorescence microscopy, library-based selections or computational protein design are advantageous but this is not required.

This full-time fixed-term post is funded by EPSRC for up to 12 months in the first instance, and is based at the Department of Biochemistry, South Parks Road, Oxford.

This position is graded on the University’s Grade 7 scale. The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

For further general information, email: mark.howarth@bioch.ox.ac.uk or phone 01865 613204, quoting reference number 135263.

Further particulars, including details of how to apply, can be obtained from the document below.

The closing date for applications is 12.00 noon on Friday 6 July 2018, with interviews for shortlisted candidates to be held as soon as possible thereafter.


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