Postdoctoral Research Associate Grade 7

You will support the Primary Principal Investigator of the UK's leading COVID-19 Clinical Neuroscience Study, COVID-CNS (£2.3M)- Dr Benedict Michael, through the National Institute for Health Research (NIHR) Health Research Health Protection Research Unit (HPRU) in Emerging and Zoonotic Infections. COVID-CNS is both a retrospective and a prospective study funded by the UKRI (£2.3M) of acute neurological complications of COVID-19 (e.g. stroke, encephalitis, psychosis) and their medium-term neurological, cognitive and psychiatric outcomes. Patients will be identified from existing studies (ISARIC and CoroNerve) and from the hospitals serving our 13 major UK university Neuroscience centres. Clinical samples of blood, cerebrospinal fluid, and neuroimaging will be obtained. Clinical data will be collected by RAs and CLRN nurses. Associated in vitro and in vivo modelling experiments will be directed by these data using in-house murine and blood brain barrier models.

You will support the programme along with a Post-Doctoral Research Fellow (in King's College London), a part-time Laboratory Technician, a Data Analyst and 6 Research Assistants (3 in Liverpool). Start date is as soon as possible. You should have a PhD in infection/immunity/molecular studies; be familiar with handling clinical samples, nucleic acid extraction, designing probes and performing RT-PCR and associated data analysis. You should have experience undertaking proteomic analysis by ELISA and ideally by bead array. Experience performing a range of molecular techniques and conducting in vitro and in vivo experiments is strongly desirable. Opportunities to visit and train in other research centres in the UK may be available. The post is available to the 22 April 2022.

The University has the right to close the vacancy early if it is deemed that there have been enough applications received

Closing date 4 January 21

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