Job description
Job summary
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A Research Associate position, is available from 28th Feb 2024. We are seeking to employ a motivated person with a background in analytical chemistry and metabolomics to support a range of exposome and toxicological analyses being conducted in within the Horizon 2020 ATHLETE consortium. The successful candidate will take up the role as an analyst in the laboratory of Dr Hector Keun and be responsible for NMR/LC-MS metabolomics/lipidomics protocol development and applications, development of data analysis and metabolite annotation pipelines, processing and annotation of metabolomics data, advise on design of biological experimental protocols, and data management.
A degree in a relevant area of science is essential, as is the ability to conduct analysis of untargeted high-resolution mass spectrometry data of human biospecimens, and experience of accurate and high-quality bioanalytical procedures according to analytical protocols, and keep good laboratory records.
The post holder will also be expected to contribute to the supervision of relevant research projects students within the Department
Duties and responsibilities
- Design and application of LC mass-spectrometry based metabolomics/lipidomics protocols using the Sciex ZenoTOF-MS platform
- Design and application of NMR based metabolomics protocols
- Data analysis of metabolite data sets and pipeline development with specific application to exposome research
Essential requirements
- PhD in an area related to metabolomics, biomarkers and metabolic biochemistry
- Practical experience within a research environment and / or publication in relevant and refereed journals
- Knowledge & experience of LC-MS based metabolomics using Sciex Zeno TOF MS
- Knowledge & experience of LC-MS based lipidomics
- Knowledge & experience of computational and statistical procedures for analysing targeted and untargeted metabolomics data
- Knowledge of metabolic biochemistry
- Knowledge & experience with mammalian cell culture and basic molecular techniques such & PCR
- Experience with preparation of human biosamples (e.g. serum/plasma)
- Knowledge & experience of NMR-based metabolomics
- Publications in LC-MS metabolomics, lipidomics and NMR based metabolomics of human biospecimens
- Knowledge of exposome research
Further information
This a full - time position (35h/pw) and a fixed-term contract (6 months).
*Candidates who have not yet been officially awarded their PhD will be appointed as a Research Assistant within the salary range £40,694 to £43,888 per annum.
Hybrid working may be considered for this role. Staff working in roles that are suitable for hybrid working will normally be expected to work 60% of their time onsite. The opportunity for hybrid working will be discussed at interview.
Should you require any further details on the role please contact: Prof Hector Keun [email protected]
The College is a proud signatory to the San-Francisco Declaration on Research Assessment (DORA),which means that in hiring and promotion decisions, we evaluate applicants on the quality of their work, not the journal impact factor where it is published. For more information, see https://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-evaluation/
The College believes that the use of animals in research is vital to improve human and animal health and welfare. Animals may only be used in research programmes where their use is shown to be necessary for developing new treatments and making medical advances. Imperial is committed to ensuring that, in cases where this research is deemed essential, all animals in the College’s care are treated with full respect, and that all staff involved with this work show due consideration at every level.
http://www.imperial.ac.uk/research-and-innovation/about-imperial-research/research-integrity/animal-research /
Imperial College is committed to equality of opportunity, to eliminating discrimination and to creating an inclusive working environment. We are an Athena SWAN Silver award winner, a Stonewall Diversity Champion, a Disability Confident Employer and work in partnership with GIRES to promote respect for trans people.
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