Understanding Mechanisms in Familial Interstitial Lung Disease Using Organoid Models
Dr Dickens and the Marciniak Group are seeking a postdoctoral researcher to drive innovation in a programme of research investigating triggers of alveolar epithelial dysfunction in familial forms of interstitial lung disease. You will work with novel alveolar organoids, creating patient-specific models which you will interrogate using innovative culture techniques, genetic manipulation and multi-omics analysis including proteomics and transcriptomics with a view to identifying novel therapeutic targets.
You should have a track record in wet-lab cell biology and possess a PhD in a relevant discipline. Prior experience of working with organoids would be an advantage, but training will be provided.
The successful applicant will join Dr Dickens, a clinician scientist, and a diverse team of basic and translational scientists and clinicians within the Marciniak Group. We are committed to promoting an exciting, rewarding and healthy working environment and strive to support the career goals of our team members.
The Cambridge Institute for Medical Research (CIMR) is located on the Cambridge Biomedical Campus and it is a collaborative institute at the interface between fundamental research and the clinic, with a mission to determine the molecular mechanisms of disease in order to advance human health.
Recent relevant papers Lim K, Rutherford EN, Sun D, Van den Boomen DJH, Edgar JR, Bang J, Matesic LE, Lee JH, Lehner PJ, Marciniak SJ, Rawlins EL, Dickens JA. A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease. BioRxiv (https://doi.org/10.1101/2023.08.30.555522 )
Dickens JA, Rutherford EN, Abreu S, Chambers JE, Ellis MO, van Schadewijk A, Hiemstra P, Marciniak SJ. Novel insights into surfactant protein C trafficking revealed through the study of a pathogenic mutant. Eur Respir J 2022;59:2100267
Please contact Dr Jenny Dickens at [email protected] for further information.
Fixed-term: The post will run for 3 years in the first instance.
We welcome applications from individuals who wish to be considered for part-time working or other flexible working arrangements.
Click the 'Apply' button below to register an account with our recruitment system (if you have not already) and apply online.
Please ensure that you upload a covering letter and a CV in the Upload section of the online application. The covering letter should outline how you match the criteria for the post and why you are applying for this role. If you upload any additional documents which have not been requested, we will not be able to consider these as part of your application.
Please include details of your referees, including email address and phone number, one of which must be your most recent line manager.
The closing date for applications is: 17th April 2024
The interview date for the role is: Beginning of May 2024
Please quote reference SC40999 on your application and in any correspondence about this vacancy.
The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.
The University has a responsibility to ensure that all employees are eligible to live and work in the UK.
Further information
Apply online
Similar Positions
-
Research Assistant (Fixed Term) , ;, United Kingdom, 25 days ago
The research assistant/outreach coordinator is required to work (for one year initially, with annual renewals and maximum of three years) on an international study funded by the US National Instit...
-
Post Doctoral Research Associate (Fixed Term) , ;, United Kingdom, 27 days ago
Fixed-term: The funds for this post are available for 1 year in the first instance. Applications are invited for a post-doctoral research associate to join Dr Jenny Zhang's team at the Department ...
-
Postdoctoral Research Associate/Fellow In Biosciences , ; University of Cambridge, United Kingdom, about 8 hours ago
This new full-time post is immediately available until 31 January 2028 on a fixed term basis. The post The Faculty wishes to recruit a Postdoctoral Research Associate or Postdoctoral Research Fell...
-
Research Assistant In Targeted Drug Delivery Validation Engineering (Fixed Term) , ;, United Kingdom, 6 days ago
Location: West Cambridge, Cambs, UK Two vacant Research Assistant positions exist, in the Department of Engineering, to work on the development of new highly targeted methods to deliver therapies ...
-
Research Assistant/Associate In Advanced Neuroimaging And Computational Neuroscience (Fixed Term) , ; University of Groningen, United Kingdom, about 8 hours ago
A position exists, for a Research Assistant/Associate in spinal/brain neuroimaging and computational neuroscience in the Department of Engineering, to work on projects related to the neural proces...
-
Research Assistant/Associate In Foreign Direct Investment Policy (Fixed Term) , ;, United Kingdom, 24 days ago
A position exists for a Research Assistant/Associate at the Institute for Manufacturing, Department of Engineering, to work on foreign direct investment policy. In particular, how the structures a...